6/7/2017
9 :00-11 :00

NMR and the Periodic Table: Part 1
Review of basics principles of multinuclear NMR, nuclear properties; Nuclei with I = ½ and quadrupole nuclei I > ½.  Structure related information in in multinuclear NMR spectra.

11/7/2017
14 :30 -17 :00

NMR and the Periodic Table: Part 2:
Isotopologues and isotopomers in NMR, chemical shift ranges and trends, heteronuclear J spin-coupling trends for selected NMR metal and non-metal I = ½ nuclei. Recording and referencing of hetero-nuclear NMR spectra. Examples of multinuclear NMR spectra and their interpretation.

12/7/2017
14 :30 -17 :00

NMR and the Periodic Table: Part 3
Use of ¹⁹⁵Pt and ¹⁰³Rh NMR as a tool for the study of the purely inorganic complexes for speciation, structural characterization of Platinum and Rhodium complexes, in the context of the separation, refining and recycling chemistry of Pt and Rh.

13/7/2017
14 :30 -17 :00

NMR and the Periodic Table: Part 4:
Illustration of selected applications of ¹⁹⁵Pt and ¹⁰³Rh NMR  in various areas such as chemical speciation in process solutions, photochemistry and platinum mirror formation.

14/07/2017
14 :30 -17 :00
 

NMR of bionorganic properties of  some water-soluble, mixed ligand complexes of Pt(II) complexes:
Cationic water-soluble Pt(II) complexes of the general structure [Pt(diimine)(L-S,O)]⁺ show remarkable aggregation behaviour in polar solvents as probed by the concentration dependence of their ¹H NMR spectra, due to strong non-covalent p-cation interactions. These complexes also show significant anti-malarial activity, particularly to chloroquine resistant strains of plasmodium falciparum. They interact strongly with DNA in aqueous solution, resulting in a significant melting point enhancement of DNA, as well anti-microbial toxicity to mutant E. coli AB1886 (uvrA). Diiffusion ordered spectroscopy (DOSY) show these complexes form large aggregates in solution