Università degli Studi di Cagliari
reserved
Complex formation equilibria of polyamine ligands with copper(II) and zinc(II)
Nurchi, Valeria M.
;Crisponi, Guido;Sanna, Gavino;
2019-01-01
Abstract
A comprehensive study of the protonation equilibria of a series of polyamine ligands along with their complex formation equilibria with Cu 2+ and Zn 2+ is reported in this work. The primary aim of this study has been the achievement of homogeneous thermodynamic data on these ligands, in order to evaluate their influence on the homeostatic equilibria of essential metal ions (Cu 2+ and Zn 2+ ) in biological fluids. These polyamines are largely used as linkers in the building of chelating agents for iron overload. Potentiometric and spectrophotometric techniques were used for the characterization of protonation and complex formation constants. In addition, the characterization of the formed complexes is discussed together with selected solid-state crystal structures, remarking the influence of the length of the chain and of the linear or tetradentate tripod nature of the polyamine ligands on the stability of the complexes.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
| JIB 2019 INMA.pdf Solo gestori archivio
Tipologia: versione editoriale
Dimensione 1.79 MB
Formato Adobe PDF
|
1.79 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.