Università degli Studi di Cagliari
Nicole Grandi
Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome
2023-01-01 Scognamiglio, Sante; Grandi, Nicole; Pessiu, Eleonora; Tramontano, Enzo
Human Endogenous Retrovirus (HERV) Transcriptome Is Dynamically Modulated during SARS-CoV-2 Infection and Allows Discrimination of COVID-19 Clinical Stages
2023-01-01 Grandi, Nicole; Erbì, Maria Chiara; Scognamiglio, Sante; Tramontano, Enzo
Prolonged activity of HERV-K(HML2) in Old World Monkeys accounts for recent integrations and novel recombinant variants
2022-01-01 Chabukswar, S.; Grandi, N.; Tramontano, E.
Genomic Snapshot of SARS-CoV-2 in Migrants Entering Through Mediterranean Sea Routes
2022-01-01 Grandi, N.; Paglietti, B.; Cusano, R.; Ibba, G.; Lai, V.; Piu, C.; Angioj, F.; Serra, C.; Kelvin, D. J.; Tramontano, E.; Rubino, S.
Enhanced antitumoral activity of TLR7 agonists via activation of human endogenous retroviruses by HDAC inhibitors
2021-01-01 Diaz-Carballo, D.; Saka, S.; Acikelli, A. H.; Homp, E.; Erwes, J.; Demmig, R.; Klein, J.; Schroer, K.; Malak, S.; D'Souza, F.; Noa-Bolano, A.; Menze, S.; Pano, E.; Andrioff, S.; Teipel, M.; Dammann, P.; Klein, D.; Nasreen, A.; Tannapfel, A.; Grandi, N.; Tramontano, E.; Ochsenfarth, C.; Strumberg, D.
Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2
2021-01-01 Fanunza, Elisa; Carletti, Fabrizio; Quartu, Marina; Grandi, Nicole; Ermellino, Laura; Milia, Jessica; Corona, Angela; Capobianchi, Maria Rosaria; Ippolito, Giuseppe; Tramontano, Enzo
INMI1 Zika Virus NS4B Antagonizes the Interferon Signaling by Suppressing STAT1 Phosphorylation
2021-01-01 Fanunza, Elisa; Grandi, Nicole; Quartu, Marina; Carletti, Fabrizio; Ermellino, Laura; Milia, Jessica; Corona, Angela; Rosaria Capobianchi, Maria; Ippolito, Giuseppe; Tramontano, Enzo
Integration of SARS-CoV-2 RNA in infected human cells by retrotransposons: an unlikely hypothesis and old viral relationships
2021-01-01 Grandi, N.; Tramontano, E.; Berkhout, B.
Human endogenous retroviruses (HERVs) and mammalian apparent Ltrs retrotransposons (MALRs) are dynamically modulated in different stages of immunity
2021-01-01 Pisano, M. P.; Grandi, N.; Tramontano, E.
Retrotransposons as drivers of Mammalian brain evolution
2021-01-01 Ferrari, R.; Grandi, N.; Tramontano, E.; Dieci, G.
HERV‐K(HML7) integrations in the human genome: Comprehensive characterization and comparative analysis in non‐human primates
2021-01-01 Grandi, N.; Pisano, M. P.; Pessiu, E.; Scognamiglio, S.; Tramontano, E.
Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase
2021-01-01 Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Ialongo, Davide; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto
Early Diffusion of SARS-CoV-2 Infection in the Inner Area of the Italian Sardinia Island
2021-01-01 Piras, Giovanna; Grandi, Nicole; Monne, Maria; Asproni, Rosanna; Fancello, Tatiana; Fiamma, Maura; Mameli, Giuseppe; Casu, Gavino; lo Maglio, Iana; Palmas, Angelo D.; Tramontano, Enzo
RNA-seq transcriptome analysis reveals long terminal repeat retrotransposon modulation in human peripheral blood mononuclear cells after in vivo lipopolysaccharide injection
2020-01-01 Pisano, M. P.; Tabone, O.; Bodinier, M.; Grandi, N.; Textoris, J.; Mallet, F.; Tramontano, E.
Diagnosi in vitro della Sclerosi Multipla
2020-01-01 Grandi, Nicole; Pisano, MARIA PAOLA; Tramontano, Enzo
Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci
2020-01-01 Grandi, Nicole; Pisano, Maria Paola; Scognamiglio, Sante; Pessiu, Eleonora; Tramontano, Enzo
Identification and characterization of ERV-W-like sequences in Platyrrhini species provides new insights into the evolutionary history of ERV-W in primates
2020-01-01 Grandi, N.; Pisano, M. P.; Demurtas, M.; Blomberg, J.; Magiorkinis, G.; Mayer, J.; Tramontano, E.
High-Throughput Sequencing is a Crucial Tool to Investigate the Contribution of Human Endogenous Retroviruses (HERVs) to Human Biology and Development
2020-01-01 Pisano, Maria Paola; Grandi, Nicole; Tramontano, Enzo
Contribution of human retroviruses to disease development-A focus on the HIV- And HERV-cancer relationships and treatment strategies
2020-01-01 Liu, C. -H.; Grandi, N.; Palanivelu, L.; Tramontano, E.; Lin, L. -T.
A human MMTV-like betaretrovirus linked to breast cancer has been present in humans at least since the Copper Age
2020-01-01 Lessi, F.; Grandi, N.; Mazzanti, C. M.; Civita, P.; Scatena, C.; Aretini, P.; Bandiera, P.; Fornaciari, A.; Giuffra, V.; Fornaciari, G.; Naccarato, A. G.; Tramontano, E.; Bevilacqua, G.
Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase
2020-01-01 Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Di Maro, Salvatore; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Valenti, Piera; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto
Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants
2020-01-01 Corona, Angela; Ballana, Ester; Distinto, Simona; Rogolino, Dominga; Del Vecchio, Claudia; Carcelli, Mauro; Badia, Roger; Riveira-Muñoz, Eva; Esposito, Francesca; Parolin, Cristina; Esté, José A; Grandi, Nicole; Tramontano, Enzo
Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors
2020-01-01 Esposito, Francesca; Sechi, Mario; Pala, Nicolino; Sanna, Adele; Koneru, Pratibha Chowdary; Kvaratskhelia, Mamuka; Naesens, Lieve; Corona, Angela; Grandi, Nicole; di Santo, Roberto; D'Amore, Vincenzo Maria; Di Leva, Francesco Saverio; Novellino, Ettore; Cosconati, Sandro; Tramontano, Enzo
Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques
2019-01-01 Costa, Giosuè; Rocca, Roberta; Corona, Angela; Grandi, Nicole; Moraca, Federica; Romeo, Isabella; Talarico, Carmine; Giovanna Gagliardi, Maria; Alessandra Ambrosio, Francesca; Ortuso, Francesco; Alcaro, Stefano; Distinto, Simona; Maccioni, Elias; Tramontano, Enzo; Artese, Anna
Comprehensive Characterization of the Human Endogenous Retrovirus HERV-K(HML-6) Group: Overview of Structure, Phylogeny, and Contribution to the Human Genome
2019-01-01 Pisano, Maria Paola; Grandi, Nicole; Cadeddu, Marta; Blomberg, Jonas; Tramontano, Enzo
The emerging field of human endogenous retroviruses: Understanding their physiological role and contribution to diseases
2019-01-01 Grandi, N.; Pisano, M. P.; Tramontano, E.
HERV-W group evolutionary history in non-human primates: Characterization of ERV-W orthologs in Catarrhini and related ERV groups in Platyrrhini
2018-01-01 Grandi, Nicole; Cadeddu, Marta; Blomberg, Jonas; Mayer, Jens; Tramontano, Enzo
Human endogenous retroviruses are ancient acquired elements still shaping innate immune responses
2018-01-01 Grandi, Nicole; Tramontano, Enzo
Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies
2018-01-01 Poongavanam, Vasanthanathan; Corona, Angela; Svendsen, Casper; Scipione, Luigi; Grandi, Nicole; Pandolfi, Fabiana; Di Santo, Roberto; Costi, Roberta; Esposito, Francesca; Tramontano, Enzo; Kongsted, Jacob
HERV envelope proteins: Physiological role and pathogenic potential in cancer and autoimmunity
2018-01-01 Grandi, Nicole; Tramontano, Enzo
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops
2018-01-01 Virgilio, Antonella; Amato, Teresa; Petraccone, Luigi; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Romero, Raquel; Haider, Shozeb; Gomez-Monterrey, Isabel; Novellino, Ettore; Mayol, Luciano; Esposito, Veronica; Galeone, Aldo
Identification and characterization of Type W Human Endogenous Retroviruses (HERV-W) in humans and comparative analysis of the group in non-human primates: new insights on HERV-W diffusion in Simiiformes and analysis of evolutionarily highly related sequences in New World Monkeys
2017-04-21
Type W Human Endogenous Retrovirus (HERV-W) Integrations and Their Mobilization by L1 Machinery: Contribution to the Human Transcriptome and Impact on the Host Physiopathology
2017-01-01 Grandi, Nicole; Tramontano, Enzo
Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion
2017-01-01 Grandi, Nicole; Cadeddu, Marta; Pisano, MARIA PAOLA; Esposito, Francesca; Blomberg, Jonas; Tramontano, Enzo
Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication
2016-01-01 Esposito, Francesca; Carli, Ilaria; Del Vecchio, Claudia; Xu, Lijia; Corona, Angela; Grandi, Nicole; Piano, Dario; Maccioni, Elias; Distinto, Simona; Parolin, Cristina; Tramontano, Enzo
Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities
2016-01-01 Pala, Nicolino; Esposito, Francesca; Rogolino, Dominga; Carcelli, Mauro; Sanna, Vanna; Palomba, Michele; Naesens, Lieve; Corona, Angela; Grandi, Nicole; Tramontano, Enzo; Sechi, Mario
Classification and characterization of human endogenous retroviruses; mosaic forms are common
2016-01-01 Vargiu, Laura; Rodriguez Tomé, P; Sperber, Go; Cadeddu, Marta; Grandi, Nicole; Blikstad, V; Tramontano, Enzo; Blomberg, J.
Contribution of type W human endogenous retroviruses to the human genome: Characterization of HERV-W proviral insertions and processed pseudogenes
2016-01-01 Grandi, Nicole; Cadeddu, Marta; Blomberg, Jonas; Tramontano, Enzo
Inhibition of HIV-1 reverse transcriptase dimerization by small molecules
2016-01-01 Tintori, C; Corona, Angela; Esposito, Francesca; Brai, A; Grandi, Nicole; Ceresola, Er; Clementi, M; Canducci, F; Tramontano, Enzo; Botta, M.
From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors
2015-01-01 Xu, L; Grandi, Nicole; Del Vecchio, C; Mandas, D; Corona, Angela; Piano, Dario; Esposito, Francesca; Parolin, C; Tramontano, Enzo
IDENTIFICATION AND GENOMIC CHARACTERIZATION OF HERV-K(HML-10) IN HUMAN GENOME GRCh37/hg19 ASSEMBLY
2014-01-01 Cadeddu, M; Grandi, Nicole; Vargiu, L; Rodriguez Tomè, P; Blomberg, J; Tramontano, E.
The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases
2014-01-01 Xu, Lijia; Grandi, Nicole; Del Vecchio, C; Corona, Angela; Mandas, D; Esposito, Francesca; Parolin, C; Tramontano, Enzo
Identification and genomic characterization of HERV-K (HML-10) in human genome GRCh37/hg19 assembly
2014-01-01 Cadeddu, Marta; Grandi, Nicole; Vargiu, L; Rodriguez Tomé, P; Blomberg, J; Tramontano, Enzo
Human Endogenous Retrovirus type W characterization in genome assembly GRCh37/hg19: an innovative approach for human diseases investigation
2014-01-01 Grandi, Nicole; Cadeddu, Marta; Vargiu, L; Rodriguez Tomé, P; Blomberg, J; Tramontano, E.
Human Endogenous Retrovirus type W distribution in the human genome: identification and characterization of a new set of proviral sequences in GRCh37/hg19 assembly
2014-01-01 Grandi, Nicole; Cadeddu, Marta; Vargiu, L; Rodriguez Tomé, P; Blomberg, J; Tramontano, Enzo
Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors
2014-01-01 Carcelli, M; Rogolino, D; Sechi, M; Rispoli, G; Fisicaro, E; Compari, C; Grandi, Nicole; Corona, Angela; Tramontano, Enzo; Pannecouque, C; Naesens, L.
IDENTIFICATION AND BIOINFORMATICS CHARACTERIZATION OF 98 HERV-K(HML-2) CONTAINING PROVIRUSES IN THE HUMAN GENOME ASSEMBLY GRCh37/hg19
2014-01-01 Cadeddu, M; Poletti, V; Grandi, Nicole; Vargiu, L; Rodriguez Tomè, P; Calistri, A; Blomberg, J; Parolin, C; Tramontano, E.
ANALYSIS OF 98 HERV-K(HML-2) CONTAINING PROVIRUSES IDENTIFIED IN THE HUMAN GENOME ASSEMBLY GRCH37/HG19 BY RETROTECTOR AND THEIR GENOMIC CONTEXT
2014-01-01 Cadeddu, Marta; Grandi, Nicole; L., Vargiu; P., Rodriguez Tomè; J., Blomberg; Tramontano, Enzo
Sennoside A, from the Traditional Chinese Medicine plant Rheum L., is a new reverse transcriptase inhibitor effective against HIV-1 replication
2014-01-01 Corona, Angela; Xu, L; Grandi, Nicole; Del Vecchio, C; Cadeddu, M; Piano, Dario; Esposito, Francesca; Parolin, C; Tramontano, E.
Recent and long-lasting infections: the need for avidity testing in HIV-1 infected subjects.
2012-01-01 Re, Mc; Bon, I; Grandi, Nicole; Miserocchi, A; Morini, S; Clo, A; Furlini, G; Gibellini, D.
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Identification, comprehensive characterization, and comparative genomics of the HERV-K(HML8) integrations in the human genome | 1-gen-2023 | Scognamiglio, Sante; Grandi, Nicole; Pessiu, Eleonora; Tramontano, Enzo | VIRUS RESEARCH | - |
| Human Endogenous Retrovirus (HERV) Transcriptome Is Dynamically Modulated during SARS-CoV-2 Infection and Allows Discrimination of COVID-19 Clinical Stages | 1-gen-2023 | Grandi, Nicole; Erbì, Maria Chiara; Scognamiglio, Sante; Tramontano, Enzo | MICROBIOLOGY SPECTRUM | - |
| Prolonged activity of HERV-K(HML2) in Old World Monkeys accounts for recent integrations and novel recombinant variants | 1-gen-2022 | Chabukswar, S.; Grandi, N.; Tramontano, E. | FRONTIERS IN MICROBIOLOGY | - |
| Genomic Snapshot of SARS-CoV-2 in Migrants Entering Through Mediterranean Sea Routes | 1-gen-2022 | Grandi, N.; Paglietti, B.; Cusano, R.; Ibba, G.; Lai, V.; Piu, C.; Angioj, F.; Serra, C.; Kelvin, D. J.; Tramontano, E.; Rubino, S. | FRONTIERS IN PUBLIC HEALTH | - |
| Enhanced antitumoral activity of TLR7 agonists via activation of human endogenous retroviruses by HDAC inhibitors | 1-gen-2021 | Diaz-Carballo, D.; Saka, S.; Acikelli, A. H.; Homp, E.; Erwes, J.; Demmig, R.; Klein, J.; Schroer, K.; Malak, S.; D'Souza, F.; Noa-Bolano, A.; Menze, S.; Pano, E.; Andrioff, S.; Teipel, M.; Dammann, P.; Klein, D.; Nasreen, A.; Tannapfel, A.; Grandi, N.; Tramontano, E.; Ochsenfarth, C.; Strumberg, D. | COMMUNICATIONS BIOLOGY | - |
| Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2 | 1-gen-2021 | Fanunza, Elisa; Carletti, Fabrizio; Quartu, Marina; Grandi, Nicole; Ermellino, Laura; Milia, Jessica; Corona, Angela; Capobianchi, Maria Rosaria; Ippolito, Giuseppe; Tramontano, Enzo | VIRULENCE | - |
| INMI1 Zika Virus NS4B Antagonizes the Interferon Signaling by Suppressing STAT1 Phosphorylation | 1-gen-2021 | Fanunza, Elisa; Grandi, Nicole; Quartu, Marina; Carletti, Fabrizio; Ermellino, Laura; Milia, Jessica; Corona, Angela; Rosaria Capobianchi, Maria; Ippolito, Giuseppe; Tramontano, Enzo | VIRUSES | - |
| Integration of SARS-CoV-2 RNA in infected human cells by retrotransposons: an unlikely hypothesis and old viral relationships | 1-gen-2021 | Grandi, N.; Tramontano, E.; Berkhout, B. | RETROVIROLOGY | - |
| Human endogenous retroviruses (HERVs) and mammalian apparent Ltrs retrotransposons (MALRs) are dynamically modulated in different stages of immunity | 1-gen-2021 | Pisano, M. P.; Grandi, N.; Tramontano, E. | BIOLOGY | - |
| Retrotransposons as drivers of Mammalian brain evolution | 1-gen-2021 | Ferrari, R.; Grandi, N.; Tramontano, E.; Dieci, G. | LIFE | - |
| HERV‐K(HML7) integrations in the human genome: Comprehensive characterization and comparative analysis in non‐human primates | 1-gen-2021 | Grandi, N.; Pisano, M. P.; Pessiu, E.; Scognamiglio, S.; Tramontano, E. | BIOLOGY | - |
| Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase | 1-gen-2021 | Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Ialongo, Davide; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto | JOURNAL OF MEDICINAL CHEMISTRY | - |
| Early Diffusion of SARS-CoV-2 Infection in the Inner Area of the Italian Sardinia Island | 1-gen-2021 | Piras, Giovanna; Grandi, Nicole; Monne, Maria; Asproni, Rosanna; Fancello, Tatiana; Fiamma, Maura; Mameli, Giuseppe; Casu, Gavino; lo Maglio, Iana; Palmas, Angelo D.; Tramontano, Enzo | FRONTIERS IN MICROBIOLOGY | - |
| RNA-seq transcriptome analysis reveals long terminal repeat retrotransposon modulation in human peripheral blood mononuclear cells after in vivo lipopolysaccharide injection | 1-gen-2020 | Pisano, M. P.; Tabone, O.; Bodinier, M.; Grandi, N.; Textoris, J.; Mallet, F.; Tramontano, E. | JOURNAL OF VIROLOGY | - |
| Diagnosi in vitro della Sclerosi Multipla | 1-gen-2020 | Grandi, Nicole; Pisano, MARIA PAOLA; Tramontano, Enzo | - | - |
| Comprehensive Analysis of HERV Transcriptome in HIV+ Cells: Absence of HML2 Activation and General Downregulation of Individual HERV Loci | 1-gen-2020 | Grandi, Nicole; Pisano, Maria Paola; Scognamiglio, Sante; Pessiu, Eleonora; Tramontano, Enzo | VIRUSES | - |
| Identification and characterization of ERV-W-like sequences in Platyrrhini species provides new insights into the evolutionary history of ERV-W in primates | 1-gen-2020 | Grandi, N.; Pisano, M. P.; Demurtas, M.; Blomberg, J.; Magiorkinis, G.; Mayer, J.; Tramontano, E. | MOBILE DNA | - |
| High-Throughput Sequencing is a Crucial Tool to Investigate the Contribution of Human Endogenous Retroviruses (HERVs) to Human Biology and Development | 1-gen-2020 | Pisano, Maria Paola; Grandi, Nicole; Tramontano, Enzo | VIRUSES | - |
| Contribution of human retroviruses to disease development-A focus on the HIV- And HERV-cancer relationships and treatment strategies | 1-gen-2020 | Liu, C. -H.; Grandi, N.; Palanivelu, L.; Tramontano, E.; Lin, L. -T. | VIRUSES | - |
| A human MMTV-like betaretrovirus linked to breast cancer has been present in humans at least since the Copper Age | 1-gen-2020 | Lessi, F.; Grandi, N.; Mazzanti, C. M.; Civita, P.; Scatena, C.; Aretini, P.; Bandiera, P.; Fornaciari, A.; Giuffra, V.; Fornaciari, G.; Naccarato, A. G.; Tramontano, E.; Bevilacqua, G. | AGING | - |
| Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase | 1-gen-2020 | Messore, Antonella; Corona, Angela; Madia, Valentina Noemi; Saccoliti, Francesco; Tudino, Valeria; De Leo, Alessandro; Scipione, Luigi; De Vita, Daniela; Amendola, Giorgio; Di Maro, Salvatore; Novellino, Ettore; Cosconati, Sandro; Métifiot, Mathieu; Andreola, Marie-Line; Valenti, Piera; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Costi, Roberta; Di Santo, Roberto | ACS MEDICINAL CHEMISTRY LETTERS | - |
| Targeting HIV-1 RNase H: N'-(2-Hydroxy-benzylidene)-3,4,5-Trihydroxybenzoylhydrazone as Selective Inhibitor Active against NNRTIs-Resistant Variants | 1-gen-2020 | Corona, Angela; Ballana, Ester; Distinto, Simona; Rogolino, Dominga; Del Vecchio, Claudia; Carcelli, Mauro; Badia, Roger; Riveira-Muñoz, Eva; Esposito, Francesca; Parolin, Cristina; Esté, José A; Grandi, Nicole; Tramontano, Enzo | VIRUSES | - |
| Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors | 1-gen-2020 | Esposito, Francesca; Sechi, Mario; Pala, Nicolino; Sanna, Adele; Koneru, Pratibha Chowdary; Kvaratskhelia, Mamuka; Naesens, Lieve; Corona, Angela; Grandi, Nicole; di Santo, Roberto; D'Amore, Vincenzo Maria; Di Leva, Francesco Saverio; Novellino, Ettore; Cosconati, Sandro; Tramontano, Enzo | ANTIVIRAL RESEARCH | - |
| Novel natural non-nucleoside inhibitors of HIV-1 reverse transcriptase identified by shape- and structure-based virtual screening techniques | 1-gen-2019 | Costa, Giosuè; Rocca, Roberta; Corona, Angela; Grandi, Nicole; Moraca, Federica; Romeo, Isabella; Talarico, Carmine; Giovanna Gagliardi, Maria; Alessandra Ambrosio, Francesca; Ortuso, Francesco; Alcaro, Stefano; Distinto, Simona; Maccioni, Elias; Tramontano, Enzo; Artese, Anna | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Comprehensive Characterization of the Human Endogenous Retrovirus HERV-K(HML-6) Group: Overview of Structure, Phylogeny, and Contribution to the Human Genome | 1-gen-2019 | Pisano, Maria Paola; Grandi, Nicole; Cadeddu, Marta; Blomberg, Jonas; Tramontano, Enzo | JOURNAL OF VIROLOGY | - |
| The emerging field of human endogenous retroviruses: Understanding their physiological role and contribution to diseases | 1-gen-2019 | Grandi, N.; Pisano, M. P.; Tramontano, E. | FUTURE VIROLOGY | - |
| HERV-W group evolutionary history in non-human primates: Characterization of ERV-W orthologs in Catarrhini and related ERV groups in Platyrrhini | 1-gen-2018 | Grandi, Nicole; Cadeddu, Marta; Blomberg, Jonas; Mayer, Jens; Tramontano, Enzo | BMC EVOLUTIONARY BIOLOGY | - |
| Human endogenous retroviruses are ancient acquired elements still shaping innate immune responses | 1-gen-2018 | Grandi, Nicole; Tramontano, Enzo | FRONTIERS IN IMMUNOLOGY | - |
| Structure-guided approach identifies a novel class of HIV-1 Ribonuclease H inhibitors: Binding mode insights through magnesium complexation and site-directed mutagenesis studies | 1-gen-2018 | Poongavanam, Vasanthanathan; Corona, Angela; Svendsen, Casper; Scipione, Luigi; Grandi, Nicole; Pandolfi, Fabiana; Di Santo, Roberto; Costi, Roberta; Esposito, Francesca; Tramontano, Enzo; Kongsted, Jacob | MEDCHEMCOMM | - |
| HERV envelope proteins: Physiological role and pathogenic potential in cancer and autoimmunity | 1-gen-2018 | Grandi, Nicole; Tramontano, Enzo | FRONTIERS IN MICROBIOLOGY | - |
| Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops | 1-gen-2018 | Virgilio, Antonella; Amato, Teresa; Petraccone, Luigi; Esposito, Francesca; Grandi, Nicole; Tramontano, Enzo; Romero, Raquel; Haider, Shozeb; Gomez-Monterrey, Isabel; Novellino, Ettore; Mayol, Luciano; Esposito, Veronica; Galeone, Aldo | SCIENTIFIC REPORTS | - |
| Identification and characterization of Type W Human Endogenous Retroviruses (HERV-W) in humans and comparative analysis of the group in non-human primates: new insights on HERV-W diffusion in Simiiformes and analysis of evolutionarily highly related sequences in New World Monkeys | 21-apr-2017 | - | - | Università degli Studi di Cagliari |
| Type W Human Endogenous Retrovirus (HERV-W) Integrations and Their Mobilization by L1 Machinery: Contribution to the Human Transcriptome and Impact on the Host Physiopathology | 1-gen-2017 | Grandi, Nicole; Tramontano, Enzo | VIRUSES | - |
| Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion | 1-gen-2017 | Grandi, Nicole; Cadeddu, Marta; Pisano, MARIA PAOLA; Esposito, Francesca; Blomberg, Jonas; Tramontano, Enzo | MOBILE DNA | - |
| Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication | 1-gen-2016 | Esposito, Francesca; Carli, Ilaria; Del Vecchio, Claudia; Xu, Lijia; Corona, Angela; Grandi, Nicole; Piano, Dario; Maccioni, Elias; Distinto, Simona; Parolin, Cristina; Tramontano, Enzo | PHYTOMEDICINE | - |
| Inhibitory effect of 2,3,5,6-tetrafluoro-4-[4-(Aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide derivatives on HIV reverse transcriptase associated rnase H activities | 1-gen-2016 | Pala, Nicolino; Esposito, Francesca; Rogolino, Dominga; Carcelli, Mauro; Sanna, Vanna; Palomba, Michele; Naesens, Lieve; Corona, Angela; Grandi, Nicole; Tramontano, Enzo; Sechi, Mario | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Classification and characterization of human endogenous retroviruses; mosaic forms are common | 1-gen-2016 | Vargiu, Laura; Rodriguez Tomé, P; Sperber, Go; Cadeddu, Marta; Grandi, Nicole; Blikstad, V; Tramontano, Enzo; Blomberg, J. | RETROVIROLOGY | - |
| Contribution of type W human endogenous retroviruses to the human genome: Characterization of HERV-W proviral insertions and processed pseudogenes | 1-gen-2016 | Grandi, Nicole; Cadeddu, Marta; Blomberg, Jonas; Tramontano, Enzo | RETROVIROLOGY | - |
| Inhibition of HIV-1 reverse transcriptase dimerization by small molecules | 1-gen-2016 | Tintori, C; Corona, Angela; Esposito, Francesca; Brai, A; Grandi, Nicole; Ceresola, Er; Clementi, M; Canducci, F; Tramontano, Enzo; Botta, M. | CHEMBIOCHEM | - |
| From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors | 1-gen-2015 | Xu, L; Grandi, Nicole; Del Vecchio, C; Mandas, D; Corona, Angela; Piano, Dario; Esposito, Francesca; Parolin, C; Tramontano, Enzo | JOURNAL OF MICROBIOLOGY | - |
| IDENTIFICATION AND GENOMIC CHARACTERIZATION OF HERV-K(HML-10) IN HUMAN GENOME GRCh37/hg19 ASSEMBLY | 1-gen-2014 | Cadeddu, M; Grandi, Nicole; Vargiu, L; Rodriguez Tomè, P; Blomberg, J; Tramontano, E. | - | - |
| The traditional Chinese medicine plant Schisandra Chinensis as source of new HIV-1 reverse transcriptase inhibitor scaffolds effective also on non-nucleoside resistant reverse transcriptases | 1-gen-2014 | Xu, Lijia; Grandi, Nicole; Del Vecchio, C; Corona, Angela; Mandas, D; Esposito, Francesca; Parolin, C; Tramontano, Enzo | - | - |
| Identification and genomic characterization of HERV-K (HML-10) in human genome GRCh37/hg19 assembly | 1-gen-2014 | Cadeddu, Marta; Grandi, Nicole; Vargiu, L; Rodriguez Tomé, P; Blomberg, J; Tramontano, Enzo | - | - |
| Human Endogenous Retrovirus type W characterization in genome assembly GRCh37/hg19: an innovative approach for human diseases investigation | 1-gen-2014 | Grandi, Nicole; Cadeddu, Marta; Vargiu, L; Rodriguez Tomé, P; Blomberg, J; Tramontano, E. | - | - |
| Human Endogenous Retrovirus type W distribution in the human genome: identification and characterization of a new set of proviral sequences in GRCh37/hg19 assembly | 1-gen-2014 | Grandi, Nicole; Cadeddu, Marta; Vargiu, L; Rodriguez Tomé, P; Blomberg, J; Tramontano, Enzo | - | - |
| Antiretroviral activity of metal-chelating HIV-1 integrase inhibitors | 1-gen-2014 | Carcelli, M; Rogolino, D; Sechi, M; Rispoli, G; Fisicaro, E; Compari, C; Grandi, Nicole; Corona, Angela; Tramontano, Enzo; Pannecouque, C; Naesens, L. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| IDENTIFICATION AND BIOINFORMATICS CHARACTERIZATION OF 98 HERV-K(HML-2) CONTAINING PROVIRUSES IN THE HUMAN GENOME ASSEMBLY GRCh37/hg19 | 1-gen-2014 | Cadeddu, M; Poletti, V; Grandi, Nicole; Vargiu, L; Rodriguez Tomè, P; Calistri, A; Blomberg, J; Parolin, C; Tramontano, E. | - | - |
| ANALYSIS OF 98 HERV-K(HML-2) CONTAINING PROVIRUSES IDENTIFIED IN THE HUMAN GENOME ASSEMBLY GRCH37/HG19 BY RETROTECTOR AND THEIR GENOMIC CONTEXT | 1-gen-2014 | Cadeddu, Marta; Grandi, Nicole; L., Vargiu; P., Rodriguez Tomè; J., Blomberg; Tramontano, Enzo | - | - |
| Sennoside A, from the Traditional Chinese Medicine plant Rheum L., is a new reverse transcriptase inhibitor effective against HIV-1 replication | 1-gen-2014 | Corona, Angela; Xu, L; Grandi, Nicole; Del Vecchio, C; Cadeddu, M; Piano, Dario; Esposito, Francesca; Parolin, C; Tramontano, E. | - | - |
| Recent and long-lasting infections: the need for avidity testing in HIV-1 infected subjects. | 1-gen-2012 | Re, Mc; Bon, I; Grandi, Nicole; Miserocchi, A; Morini, S; Clo, A; Furlini, G; Gibellini, D. | NEW MICROBIOLOGICA | - |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile