Comparative biopharmaceutical properties of commercial lorazepam tablets

BAROLI, BIANCA MARIA;FADDA, ANNA MARIA;MACCIONI AM;SINICO C;VALENTI D.

1996-01-01

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Abstract

The biopharmaceutical properties of eight lorazepam tablet formulations, marketed in Italy, were studied and compared. A few significant differences in behaviour were found even among similar formulations. In vitro dissolution patterns vazied on varying pH, technological properties, excipients employed and active ingredient concentrations.