Pistacia lentiscus L. essential oil inhibits cotton pellet granuloma in rats: involvement of IL-6 and TNF-a

MAXIA, ANDREA;Frau MA;PIRAS, ALESSANDRA;SANNA, CINZIA;Karchuli MS;Kasture V.

2011-01-01

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Abstract

Essential oil of Pistacia lentiscus L. inhibits carrageenan-induced inflammation in rats. Orhan et al. have reported that a-pinene is responsible for the antinflammatory activity. In the present study we report inhibitory effect of P. lentiscus essential oil in cotton pellet-induced granuloma and reduction in serum level of interleukin-6 (IL-6) and tumor necrosis factor-a (TNF-a)