Andrea Pinna
Insights into the interaction between lipid bilayers and trehalose aqueous solutions
Kumar A.;Cincotti A.;
2020-01-01
Abstract
The properties of lipid bilayers in contact with trehalose solutions in water were studied in the full concentration range using molecular dynamics simulations. The mechanism of trehalose interaction with the bilayer surface was analysed considering hydrogen bonding and molecular arrangements as well as the possible changes in bilayer properties. The effect of concentration of the possible mechanisms of trehalose action as membrane protectant were discussed to infer the possible evolution of water replacement by trehalose at the membrane surface and its relationship with the trehalose role in anhydrobiosis and drying processes.File | Dimensione | Formato | |
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2020, Journal of Molecular Liquids, 113639.pdf Solo gestori archivio
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Tipologia: versione editoriale
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