Synthesis of β-sulfinyl cyclobutane carboxylic amides: Via a formal α to β sulphoxide migration process

Ghisu L.;Melis N.;Serusi L.;Luridiana A.;Soddu F.;Secci F.;Caboni P.;Frongia A.
Supervision
2019-01-01

Abstract

An original tandem reaction consisting of a thermal elimination-addition process was developed. Highly substituted β-sulfinyl cyclobutane carboxylic acid derivatives were obtained from isomeric α-sulfinyl derivatives in a single operation in good to high yields and with high trans diastereoselectivity.
2019
2019
Inglese
ORGANIC & BIOMOLECULAR CHEMISTRY
17
25
6143
6147
5
WOS:000473052800007
2-s2.0-85068025877
31180093
http://pubs.rsc.org/en/journals/journal/ob
https://pubs.rsc.org/en/content/articlelanding/2019/OB/C9OB00758J#!divAbstract
Esperti anonimi
internazionale
scientifica
CATALYTIC ENANTIOSELECTIVE SYNTHESIS; DONOR-ACCEPTOR CYCLOBUTANES; CIS/TRANS STEREOCHEMISTRY; AMPHIPHILES INFLUENCE; ASYMMETRIC-SYNTHESIS; SULFENIC ACIDS; DERIVATIVES; INHIBITORS; CYCLOADDITIONS; FOLDAMERS
sì
Ghisu, L.; Melis, N.; Serusi, L.; Luridiana, A.; Soddu, F.; Secci, F.; Caboni, P.; Guillot, R.; Aitken, D. J.; Frongia, A.
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
10
reserved
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