Epithelial-mesenchymal transition as a target for botanicals in cancer metastasis

Zucca, Paolo
;
2019-01-01

Abstract

Background: The plant kingdom represents an unlimited source of phytotherapeutics with promising perspectives in the field of anticancer drug discovery. Purpose: In this view, epithelial-mesenchymal transition (EMT) represents a novel and major target in anticancer therapy. Therefore, this narrative review aims to provide an updated overview on the bioactive phytochemicals with anti-EMT activity. Conclusion: Among the plant products reviewed, phenylpropanoids were the most investigated at preclinical phase, thus exhibiting a promising potential as anticancer drugs, though an evidence-based clinical efficacy is still lacking.
2019
2019
Inglese
PHYTOMEDICINE
55
125
136
12
WOS:000462767700014
2-s2.0-85056208140
30668422
www.urbanfischer.de/journals/phytomed
https://www.sciencedirect.com/science/article/pii/S0944711318302538
Esperti anonimi
internazionale
scientifica
Alkaloids; Anticancer phytotherapeutics; Bioactive phytochemicals; Chemoprevention; Isoprenoids; Phenylpropanoids; Molecular Medicine; Pharmacology; Drug Discovery; Pharmaceutical Science; Complementary and Alternative Medicine; Dermatology;
sì
Salehi, Bahare; Varoni, Elena Maria; Sharifi-Rad, Mehdi; Rajabi, Sadegh; Zucca, Paolo; Iriti, Marcello; Sharifi-Rad, Javad
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
7
reserved
File in questo prodotto:
File Dimensione Formato  
Salehi 2019.pdf

Solo gestori archivio

Descrizione: MS post print
Tipologia: versione post-print
Dimensione 1.78 MB
Formato Adobe PDF
  Visualizza/Apri   Richiedi una copia
1.78 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Questionario e social

Condividi su:
Impostazioni cookie