On the Prediction and Shaping of the PSD in Crystallization Operations

GROSSO, MASSIMILIANO;BARATTI, ROBERTO;
2010-01-01

Abstract

The time behavior of the crystal size distribution in anti-solvent based crystal growth processes is investigated via statistical tools. The data are provided by the NaCl-water- ethanol anti-solvent crystallization system in a bench-scale fed-batch crystallization unit. It was found that the crystal population can be reasonably described in terms of a Gaussian or a Gamma distribution depending on the operating conditions.
2010
978-0-444-53569-6
Anti-solvent crystallization; maximum likelihood estimation; particle size distribution
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