Clinical correlates of age at onset distribution in bipolar disorder: a comparison between diagnostic subgroups

MANCHIA, MIRKO;Maina, Giuseppe;CARPINIELLO, BERNARDO;PINNA, FEDERICA;Steardo, Luca;D'Ambrosio, Virginia;Salvi, Virginio;Alda, Martin;TORTORELLA, ALFONSO;Albert, Umberto

2017-01-01

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Abstract

Admixture analysis of age at onset (AAO) has helped delineating the clinical profile of early onset (EO) bipolar disorder (BD). However, there is scarce evidence comparing the distributional properties of AAO as well as the clinical features of EO BD type 1 (BD1) with EO BD type 2 (BD2). To this end, we studied 515 BD patients (224 BD1, 279 BD2, and 12 BD not otherwise specified [NOS]) diagnosed according to DSM-IV-TR criteria.