Francesca Marcello
Compositional profile of ovine milk with a high somatic cell count: A metabolomics approach
CABONI, PIERLUIGI;Manis, C;CORONEO, VALENTINA;SCANO, PAOLA
2017-01-01
Abstract
Ovine milk (Sarda breed) with high somatic cell count (SCC) (>1 x 106 cell mL-1) was compared with similar milk of low SCC (<150 x 103 cell mL-1) using a metabolomics approach, whereby the metabolite profile of milk was studied by gas chromatography coupled to mass spectrometry. Discriminant analysis indicated that high SCC milk samples have metabolite profiles from those of low SCC samples. Malic acid, ribitol, glucose and medium-short chain fatty acids were up-regulated in milk with high SCC, while stearic acid, oleic acid, scyllo-inositol, glutamine, threonine, and glycine were down-regulated. These differences may be related to metabolite release by somatic cells, inflammation status, altered permeability of the udder tight junctions, and changes in milk osmotic equilibrium. Moreover, high SCC milk samples showed higher levels of proteins, casein and fat, lower concentrations of lactose and urea, and a different fatty acid profile from that of low SCC milkFile | Dimensione | Formato | |
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