An Environmentally Sustainable Mechanochemical Route to Hydroxamic Acid Derivatives

MOCCI, RITA;Luca, Lidia De;DELOGU, FRANCESCO;PORCHEDDU, ANDREA

2016-01-01

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Abstract

An operationally simple, and cost efficient conversion of carboxylic acids into hydroxamic acid derivatives via a high-energy mechanochemical activation is presented. This ball milling methodology was applied to a wide variety of carboxylic acids dramatically improving purification issues associated with this class of molecules, which still remain one of the main bottlenecks of classical methodologies. (Figure presented.).