Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis

MELEDDU, RITA;DE LOGU, ALESSANDRO;
2009-01-01

Abstract

A series of novel enantiomerically pure azole derivatives was synthesized. The new compounds, bearing both an imidazole as well as a triazole moiety, were evaluated as antimycobacterial agents. One of them proved to have activity against Mycobaterium tuberculosis comparable to those of the classical antibacterial/antifungal drugs Econazole and Clotrimazole.
2009
19
2203
2205
3
Sì, ma tipo non specificato
Castagnolo, D; Radi, M; Dessì, F; Manetti, F; Saddi, M; Meleddu, Rita; DE LOGU, Alessandro; Botta, M.
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
8
none
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