New cytotoxic saturated and unsaturated cyclohexanones from Anthemis maritima

CASU, MARIANO;FLORIS, COSTANTINO;COTTIGLIA, FILIPPO
2008-01-01

Abstract

Two new cyclohexenones (antheminones A and B) and a new cyclohexanone, (antheminone C) along with five known compounds were isolated from the leaves of Anthemis maritima L. The structures were mainly deduced from extensive 1D and 2D NMR spectroscopy and mass spectrometry. The new compounds were tested in vitro for their cytotoxic activity against adherent and non-adherent cancer cell lines. Antheminones A and C exhibited significant antiproliferative activity against leukemia cells with IC50 values ranging from 3.2 to 14 lM.
2008
18
5
1559
1562
4
WOS:000254180200003
2-s2.0-40149087056
Esperti anonimi
Collu, F; Bonsignore, L; Casu, Mariano; Floris, Costantino; Gertschcjurg, ; Cottiglia, Filippo
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
6
none
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