Tryptophan-deficient diet increases the neurochemical and behavioral response to amphetamine

CARTA, MANOLO;STANCAMPIANO, ROBERTO
2006-01-01

Abstract

The present study examined the effects of a tryptophan-deficient diet on behavioral and neurochemical response to amphetamine. A tryptophan-deficient diet (14 days) decreased striatal serotonin and 5-hydroxyindolacetic acid content in rats. Under the latter conditions, amphetamine increased dopamine efflux in striatum and nucleus accumbens and produced a greater increase in motor activity when compared to controls. These results indicate how response to psychostimulants might be altered in the presence of a tryptophan-deficient diet.
2006
BRAIN RESEARCH
1094
86
91
6
WOS:000239068400009
2-s2.0-33745276277
Esperti anonimi
Carta, Manolo; Fadda, F; Stancampiano, Roberto
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
3
none
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