Università degli Studi di Cagliari
Marta Anna Kowalik
Metabolic reprogramming in Nrf2-driven proliferation of normal rat hepatocytes
2024-01-01 Kowalik, M. A.; Taguchi, K.; Serra, M.; Caddeo, A.; Puliga, E.; Bacci, M.; Koshiba, S.; Inoue, J.; Hishinuma, E.; Morandi, A.; Giordano, S.; Perra, A.; Yamamoto, M.; Columbano, A.
Sex difference in liver diseases: How preclinical models help to dissect the sex-related mechanisms sustaining NAFLD and hepatocellular carcinoma
2023-01-01 Smiriglia, A.; Lorito, N.; Serra, M.; Perra, A.; Morandi, A.; Kowalik, M. A.
Potential use of TG68 - A novel thyromimetic - for the treatment of non-alcoholic fatty liver (NAFLD)-associated hepatocarcinogenesis
2023-01-01 Caddeo, A.; Serra, M.; Sedda, F.; Bacci, A.; Manera, C.; Rapposelli, S.; Columbano, A.; Perra, A.; Kowalik, M. A.
The density of hepatic autonomic innervation differs between compensatory and direct hyperplasia rat models
2023-01-01 Trucas, M.; Kowalik, M. A.; Boi, M.; Serra, M. P.; Perra, A.; Quartu, M.
Multi-Organ Morphological Findings in a Humanized Murine Model of Sickle Cell Trait
2023-01-01 Trucas, Marcello; Burattini, Sabrina; Porcu, Susanna; Simbula, Michela; Ristaldi, Maria Serafina; Kowalik, Marta Anna; Serra, Maria Pina; Gobbi, Pietro; Battistelli, Michela; Perra, Andrea; Quartu, Marina
Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model
2022-01-01 Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea
Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model
2022-01-01 Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea
Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model
2022-01-01 Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea
Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCC
2022-01-01 Mattu, Sandra; Zavattari, Patrizia; Kowalik, Marta Anna; Serra, Marina; Sulas, Pia; Pal, Rajesh; Puliga, Elisabetta; Sutti, Salvatore; Foglia, Beatrice; Parola, Maurizio; Albano, Emanuele; Giordano, Silvia; Perra, Andrea; Columbano, Amedeo
mRNA-miRNA networks identify metabolic pathways associated to the anti-tumorigenic effect of thyroid hormone on preneoplastic nodules and hepatocellular carcinoma
2022-01-01 Serra, Marina; Pal, Rajesh; Puliga, Elisabetta; Sulas, Pia; Cabras, Lavinia; Cusano, Roberto; Giordano, Silvia; Perra, Andrea; Columbano, Amedeo; Kowalik, Marta Anna
The double-sided of human leukocyte antigen-G molecules in type 1 autoimmune hepatitis
2022-01-01 Littera, Roberto; Perra, Andrea; Miglianti, Michela; Piras, Ignazio S; Mocci, Stefano; Lai, Sara; Melis, Maurizio; Zolfino, Teresa; Balestrieri, Cinzia; Conti, Maria; Serra, Giancarlo; Figorilli, Francesco; Firinu, Davide; Onali, Simona; Matta, Laura; Porcu, Carmen; Pes, Francesco; Fanni, Daniela; Manieli, Cristina; Vacca, Monica; Cusano, Roberto; Trucas, Marcello; Cipri, Selene; Tranquilli, Stefania; Rassu, Stefania; Cannas, Federica; Carta, Mauro Giovanni; Kowalik, Marta Anna; Giuressi, Erika; Faa, Gavino; Chessa, Luchino; Giglio, Sabrina
Diverse MicroRNAs-mRNA networks regulate the priming phase of mouse liver regeneration and of direct hyperplasia
2022-01-01 Pal, Rajesh; Kowalik, MARTA ANNA; Serra, Marina; Migliore, Cristina; Giordano, Silvia; Columbano, Amedeo; Perra, Andrea
Novel thyroid hormone receptor beta agonist TG68 safely induces hepatic fat loss reduction in a NASH mouse model
2021-01-01 Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Runfola, Massimiliano; Bacci, Andrea; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea
Tg68, a novel thyroid hormone receptor‐β agonist for the treatment of NAFLD
2021-01-01 Caddeo, A.; Kowalik, M. A.; Serra, M.; Runfola, M.; Bacci, A.; Rapposelli, S.; Columbano, A.; Perra, A.
Delta-globin gene expression improves sickle cell disease in a humanised mouse model
2021-01-01 Porcu, Susanna; Simbula, Michela; Marongiu, Maria F; Perra, Andrea; Poddie, Daniela; Perseu, Lucia; Kowalik, Marta A; Littera, Roberto; Barella, Susanna; Caria, Cristian A; Demartis, Franca R; Ristaldi, Maria S
Natural killer-cell immunoglobulin-like receptors trigger differences in immune response to SARS-CoV-2 infection
2021-01-01 Littera, Roberto; Chessa, Luchino; Deidda, Silvia; Angioni, Goffredo; Campagna, Marcello; Lai, Sara; Melis, Maurizio; Cipri, Selene; Firinu, Davide; Santus, Simonetta; Lai, Alberto; Porcella, Rita; Rassu, Stefania; Meloni, Federico; Schirru, Daniele; Cordeddu, William; Kowalik, MARTA ANNA; Ragatzu, Paola; Vacca, Monica; Cannas, Federica; Alba, Francesco; Carta, Mauro; DEL GIACCO, Stefano; Restivo, Angelo; Deidda, Simona; Palimodde, Antonella; Congera, Paola; Perra, Roberto; Orru, Germano; Pes, Francesco; Loi, Martina; Murru, Claudia; Urru, Enrico; Onali, Simona; Coghe, Ferdinando; Giglio, SABRINA RITA; Perra, Andrea
Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration
2020-01-01 Perra, A.; Kowalik, M. A.; Cabras, L.; Runfola, M.; Sestito, S.; Migliore, C.; Giordano, S.; Chiellini, G.; Rapposelli, S.; Columbano, A.
Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience
2020-01-01 Littera, Roberto; Campagna, Marcello; Deidda, Silvia; Angioni, Goffredo; Cipri, Selene; Melis, Maurizio; Firinu, Davide; Santus, Simonetta; Lai, Alberto; Porcella, Rita; Lai, Sara; Rassu, Stefania; Scioscia, Rosetta; Meloni, Federico; Schirru, Daniele; Cordeddu, William; Kowalik, MARTA ANNA; Serra, Maria; Ragatzu, Paola; Carta, Mauro; DEL GIACCO, Stefano; Restivo, Angelo; Deidda, Simona; Sandro, Orrù; Palimodde, Antonella; Perra, Roberto; Orru, Germano; Conti, Maria; Balestrieri, Cinzia; Serra, Giancarlo; Onali, Simona; Marongiu, Francesco; Perra, Andrea; Chessa, Luchino
Animal models: A useful tool to unveil metabolic changes in hepatocellular carcinoma
2020-01-01 Serra, M.; Columbano, A.; Perra, A.; Kowalik, M. A.
Distinct Mechanisms Are Responsible for Nrf2-Keap1 Pathway Activation at Different Stages of Rat Hepatocarcinogenesis
2020-01-01 Orrù, Claudia; Perra, Andrea; Kowalik, Marta Anna; Rizzolio, Sabrina; Puliga, Elisabetta; Cabras, Lavinia; Giordano, Silvia; Columbano, Amedeo
Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming
2020-01-01 Kowalik, M. A.; Puliga, E.; Cabras, L.; Sulas, P.; Petrelli, A.; Perra, A.; Ledda-Columbano, G. M.; Morandi, A.; Merlin, S.; Orru, C.; Sanchez-Martin, C.; Fornari, F.; Gramantieri, L.; Parri, M.; Rasola, A.; Bellomo, S. E.; Sebastian, C.; Follenzi, A.; Giordano, S.; Columbano, A.
Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis
2020-01-01 Runfola, M.; Sestito, S.; Bellusci, L.; La Pietra, V.; D'Amore, V. M.; Kowalik, M. A.; Chiellini, G.; Gul, S.; Perra, A.; Columbano, A.; Marinelli, L.; Novellino, E.; Rapposelli, S.
THYROID HORMONE INHIBITS HEPATOCELLULAR CARCINOMA (HCC) DEVELOPMENT BY INTERFERING WITH THE METABOLIC PROFILE OF CANCER CELLS
2018-01-01 Serra, Marina; Cabras, Lavinia; Kowalik, MARTA ANNA; Perra, Andrea; Sanchez-Martin, Carlos; Rasola, Andrea; Columbano, Amedeo
High frequency of β-catenin mutations in mouse hepatocellular carcinomas induced by a nongenotoxic constitutive androstane receptor agonist
2018-01-01 Mattu, Sandra; Saliba, Christian; Sulas, Pia; Zavattari, Patrizia; Perra, Andrea; Kowalik, Marta A.; Monga, Satdarshan P.; Columbano, Amedeo
Thyroid hormones, thyromimetics and their metabolites in the treatment of liver disease
2018-01-01 Kowalik, Marta A.; Columbano, Amedeo; Perra, Andrea
Emerging role of the pentose phosphate pathway in hepatocellular carcinoma
2017-01-01 Kowalik, Marta Anna; Columbano, Amedeo; Perra, Andrea
Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis
2016-01-01 Kowalik, MARTA ANNA; Guzzo, Giulia; Morandi, Andrea; Perra, Andrea; Menegon, Silvia; Masgras, Ionica; Trevisan, Elena; Angioni, MARIA MADDALENA; Fornari, Francesca; Quagliata, Luca; Ledda, GIOVANNA MARIA; Gramantieri, Laura; Terracciano, Luigi; Giordano, Silvia; Chiarugi, Paola; Rasola, Andrea; Columbano, Amedeo
Induction of autophagy promotes the growth of early preneoplastic rat liver nodules
2016-01-01 Kowalik, MARTA ANNA; Perra, Andrea; Ledda, GIOVANNA MARIA; Ippolito, G; Piacentini, M; Columbano, Amedeo; Falasca, L.
Statistical health monitoring applied to a metabolomic study of experimental hepatocarcinogenesis: an alternative approach to supervised methods for the identification of false positives
2016-01-01 DEL CARRATORE, Francesco; Lussu, Milena; Kowalik, MARTA ANNA; Perra, Andrea; Griffin, Jl; Atzori, Luigi; Grosso, Massimiliano
Global gene expression profile of normal and regenerating liver in young and old mice
2015-01-01 Pibiri, Monica; Sulas, Pia; Leoni, VERA PIERA; Perra, Andrea; Kowalik, MARTA ANNA; Cordella, Angela; Saggese, Pasquale; Nassa, Giovanni; Ravo, Maria
Reply to: "YAP in tumorigenesis: Friend or foe?"
2015-01-01 Perra, Andrea; Kowalik, MARTA ANNA; Giordano, S; Columbano, Amedeo
Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis
2015-01-01 Zavattari, Patrizia; Perra, Andrea; Menegon, S; Kowalik, MARTA ANNA; Petrelli, A; Angioni, MARIA MADDALENA; Follenzi, A; Quagliata, L; Ledda, GIOVANNA MARIA; Terracciano, L; Giordano, S; Columbano, Amedeo
Cytokeratin-19 positivity is acquired along cancer progression and does not predict cell origin in rat hepatocarcinogenesis
2015-01-01 Kowalik, MARTA ANNA; Sulas, Pia; Ledda, GIOVANNA MARIA; Giordano, S; Columbano, Amedeo; Perra, Andrea
Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats
2015-01-01 Frau, C; Loi, Roberto; Petrelli, A; Perra, Andrea; Menegon, S; Kowalik, MARTA ANNA; Pinna, S; Leoni, VERA PIERA; Fornari, F; Gramantieri, L; Ledda, GIOVANNA MARIA; Giordano, S; Columbano, Amedeo
YAP activation is an early event and a potential therapeutic target in liver cancer development
2014-01-01 Perra, Andrea; Kowalik, Ma; Ghiso, E; Ledda, GIOVANNA MARIA; Di Tommaso, L; Angioni, MARIA MADDALENA; Raschioni, C; Testore, E; Roncalli, M; Giordano, S; Columbano, Amedeo
MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC).
2014-01-01 Petrelli, A; Perra, Andrea; Cora, D; Sulas, P; Menegon, S; Manca, C; Migliore, C; Kowalik M., A; Ledda, GIOVANNA MARIA; Giordano, S; Columbano, Amedeo
Transcription profiling by array of mouse liver from TCPOBOP treated wild type and c-jun conditional knockout animals.
2012-01-01 Leoni, Vp; Ledda, GIOVANNA MARIA; Pibiri, Monica; Saliba, C; Perra, Andrea; Kowalik, Ma; Grober Oli, Mv; Ravo, M; Weisz, A; Ghiso, E; Giordano, S; Columbano, A.
Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3
2011-01-01 Leoni, VERA PIERA; Ledda, GIOVANNA MARIA; Pibiri, Monica; Saliba, C; Perra, Andrea; Kowalik, MARTA ANNA; Grober, Om; Ravo, M; Weisz, A; Locker, J; Ghiso, E; Giordano, S; Columbano, Amedeo
Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice
2011-01-01 Kowalik, MARTA ANNA; Saliba, C; Pibiri, Monica; Perra, Andrea; Ledda, GIOVANNA MARIA; Sarotto, I; Ghiso, E; Giordano, S; Columbano, Amedeo
Reply to: Clinical correlation of miR-375 and alpha-fetoprotein in hepatocellular carcinoma: comparison in mice and humans
2011-01-01 Kowalik, MARTA ANNA; Ledda, GIOVANNA MARIA; Giordano, S; Columbano, Amedeo
Gender-specific interplay of signaling through β-catenin and CAR in the regulation of xenobiotic-induced hepatocyte proliferation
2011-01-01 Braeuning, A; Heubach, Y; Knorpp, T; Kowalik, MARTA ANNA; Templin, M; Columbano, Amedeo; Schwarz, M.
TRbeta is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells
2010-01-01 Kowalik, MARTA ANNA; Perra, Andrea; Pibiri, Monica; Cocco, Mt; Samarut, J; Plateroti, M; Ledda, GIOVANNA MARIA; Columbano, Amedeo
Effect of the ligands of thyroid hormone receptor on non-alcoholic fatty liver disease
2009-01-23
Early metabolic changes in a liver carcinogenesis model
2009-01-01 Atzori, Luigi; Weljie, Am; Kowalik, M; Perra, Andrea; Columbano, A; Griffin, Jl
Early Metabolic Changes in preneoplastc nodules of the liver
2009-01-01 Weljie, ; Kowalik, M; Perra, Andrea; Columbano, A; Griffin, Jl; Atzori, Luigi
Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype
2009-01-01 Perra, Andrea; Kowalik, MARTA ANNA; Pibiri, Monica; Ledda, GIOVANNA MARIA; Columbano, Amedeo
Characterization Of Early Stage Metabolic Perturbations In A Rat Model Of Hepatocellular Carcinogenesis
2008-01-01 Weljie, A; Kowalik, M; Atzori, Luigi; Griffin, Jl
Thyroid hormone (T3) and TRbeta agonist GC-1 inhibit/reverse nonalcoholic fatty liver in rats
2008-01-01 Perra, Andrea; Simbula, Gabriella; Simbula, M; Pibiri, Monica; Kowalik, MARTA ANNA; Sulas, P; Cocco, Mt; Ledda, GIOVANNA MARIA; Columbano, Amedeo
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Metabolic reprogramming in Nrf2-driven proliferation of normal rat hepatocytes | 1-gen-2024 | Kowalik, M. A.; Taguchi, K.; Serra, M.; Caddeo, A.; Puliga, E.; Bacci, M.; Koshiba, S.; Inoue, J.; Hishinuma, E.; Morandi, A.; Giordano, S.; Perra, A.; Yamamoto, M.; Columbano, A. | HEPATOLOGY | - |
| Sex difference in liver diseases: How preclinical models help to dissect the sex-related mechanisms sustaining NAFLD and hepatocellular carcinoma | 1-gen-2023 | Smiriglia, A.; Lorito, N.; Serra, M.; Perra, A.; Morandi, A.; Kowalik, M. A. | ISCIENCE | - |
| Potential use of TG68 - A novel thyromimetic - for the treatment of non-alcoholic fatty liver (NAFLD)-associated hepatocarcinogenesis | 1-gen-2023 | Caddeo, A.; Serra, M.; Sedda, F.; Bacci, A.; Manera, C.; Rapposelli, S.; Columbano, A.; Perra, A.; Kowalik, M. A. | FRONTIERS IN ONCOLOGY | - |
| The density of hepatic autonomic innervation differs between compensatory and direct hyperplasia rat models | 1-gen-2023 | Trucas, M.; Kowalik, M. A.; Boi, M.; Serra, M. P.; Perra, A.; Quartu, M. | JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM | - |
| Multi-Organ Morphological Findings in a Humanized Murine Model of Sickle Cell Trait | 1-gen-2023 | Trucas, Marcello; Burattini, Sabrina; Porcu, Susanna; Simbula, Michela; Ristaldi, Maria Serafina; Kowalik, Marta Anna; Serra, Maria Pina; Gobbi, Pietro; Battistelli, Michela; Perra, Andrea; Quartu, Marina | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model | 1-gen-2022 | Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea | - | - |
| Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model | 1-gen-2022 | Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea | - | - |
| Novel thyroid hormone receptor-beta agonist TG68 safely induces hepatic fat reduction in a non-alcoholic steatohepatitis rat model | 1-gen-2022 | Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea | - | - |
| Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCC | 1-gen-2022 | Mattu, Sandra; Zavattari, Patrizia; Kowalik, Marta Anna; Serra, Marina; Sulas, Pia; Pal, Rajesh; Puliga, Elisabetta; Sutti, Salvatore; Foglia, Beatrice; Parola, Maurizio; Albano, Emanuele; Giordano, Silvia; Perra, Andrea; Columbano, Amedeo | CMGH | - |
| mRNA-miRNA networks identify metabolic pathways associated to the anti-tumorigenic effect of thyroid hormone on preneoplastic nodules and hepatocellular carcinoma | 1-gen-2022 | Serra, Marina; Pal, Rajesh; Puliga, Elisabetta; Sulas, Pia; Cabras, Lavinia; Cusano, Roberto; Giordano, Silvia; Perra, Andrea; Columbano, Amedeo; Kowalik, Marta Anna | FRONTIERS IN ONCOLOGY | - |
| The double-sided of human leukocyte antigen-G molecules in type 1 autoimmune hepatitis | 1-gen-2022 | Littera, Roberto; Perra, Andrea; Miglianti, Michela; Piras, Ignazio S; Mocci, Stefano; Lai, Sara; Melis, Maurizio; Zolfino, Teresa; Balestrieri, Cinzia; Conti, Maria; Serra, Giancarlo; Figorilli, Francesco; Firinu, Davide; Onali, Simona; Matta, Laura; Porcu, Carmen; Pes, Francesco; Fanni, Daniela; Manieli, Cristina; Vacca, Monica; Cusano, Roberto; Trucas, Marcello; Cipri, Selene; Tranquilli, Stefania; Rassu, Stefania; Cannas, Federica; Carta, Mauro Giovanni; Kowalik, Marta Anna; Giuressi, Erika; Faa, Gavino; Chessa, Luchino; Giglio, Sabrina | FRONTIERS IN IMMUNOLOGY | - |
| Diverse MicroRNAs-mRNA networks regulate the priming phase of mouse liver regeneration and of direct hyperplasia | 1-gen-2022 | Pal, Rajesh; Kowalik, MARTA ANNA; Serra, Marina; Migliore, Cristina; Giordano, Silvia; Columbano, Amedeo; Perra, Andrea | CELL PROLIFERATION | - |
| Novel thyroid hormone receptor beta agonist TG68 safely induces hepatic fat loss reduction in a NASH mouse model | 1-gen-2021 | Caddeo, ANDREA MARCO; Kowalik, MARTA ANNA; Serra, Marina; Runfola, Massimiliano; Bacci, Andrea; Rapposelli, Simona; Columbano, Amedeo; Perra, Andrea | - | - |
| Tg68, a novel thyroid hormone receptor‐β agonist for the treatment of NAFLD | 1-gen-2021 | Caddeo, A.; Kowalik, M. A.; Serra, M.; Runfola, M.; Bacci, A.; Rapposelli, S.; Columbano, A.; Perra, A. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Delta-globin gene expression improves sickle cell disease in a humanised mouse model | 1-gen-2021 | Porcu, Susanna; Simbula, Michela; Marongiu, Maria F; Perra, Andrea; Poddie, Daniela; Perseu, Lucia; Kowalik, Marta A; Littera, Roberto; Barella, Susanna; Caria, Cristian A; Demartis, Franca R; Ristaldi, Maria S | BRITISH JOURNAL OF HAEMATOLOGY | - |
| Natural killer-cell immunoglobulin-like receptors trigger differences in immune response to SARS-CoV-2 infection | 1-gen-2021 | Littera, Roberto; Chessa, Luchino; Deidda, Silvia; Angioni, Goffredo; Campagna, Marcello; Lai, Sara; Melis, Maurizio; Cipri, Selene; Firinu, Davide; Santus, Simonetta; Lai, Alberto; Porcella, Rita; Rassu, Stefania; Meloni, Federico; Schirru, Daniele; Cordeddu, William; Kowalik, MARTA ANNA; Ragatzu, Paola; Vacca, Monica; Cannas, Federica; Alba, Francesco; Carta, Mauro; DEL GIACCO, Stefano; Restivo, Angelo; Deidda, Simona; Palimodde, Antonella; Congera, Paola; Perra, Roberto; Orru, Germano; Pes, Francesco; Loi, Martina; Murru, Claudia; Urru, Enrico; Onali, Simona; Coghe, Ferdinando; Giglio, SABRINA RITA; Perra, Andrea | PLOS ONE | - |
| Potential role of two novel agonists of thyroid hormone receptor-β on liver regeneration | 1-gen-2020 | Perra, A.; Kowalik, M. A.; Cabras, L.; Runfola, M.; Sestito, S.; Migliore, C.; Giordano, S.; Chiellini, G.; Rapposelli, S.; Columbano, A. | CELL PROLIFERATION | - |
| Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience | 1-gen-2020 | Littera, Roberto; Campagna, Marcello; Deidda, Silvia; Angioni, Goffredo; Cipri, Selene; Melis, Maurizio; Firinu, Davide; Santus, Simonetta; Lai, Alberto; Porcella, Rita; Lai, Sara; Rassu, Stefania; Scioscia, Rosetta; Meloni, Federico; Schirru, Daniele; Cordeddu, William; Kowalik, MARTA ANNA; Serra, Maria; Ragatzu, Paola; Carta, Mauro; DEL GIACCO, Stefano; Restivo, Angelo; Deidda, Simona; Sandro, Orrù; Palimodde, Antonella; Perra, Roberto; Orru, Germano; Conti, Maria; Balestrieri, Cinzia; Serra, Giancarlo; Onali, Simona; Marongiu, Francesco; Perra, Andrea; Chessa, Luchino | FRONTIERS IN IMMUNOLOGY | - |
| Animal models: A useful tool to unveil metabolic changes in hepatocellular carcinoma | 1-gen-2020 | Serra, M.; Columbano, A.; Perra, A.; Kowalik, M. A. | CANCERS | - |
| Distinct Mechanisms Are Responsible for Nrf2-Keap1 Pathway Activation at Different Stages of Rat Hepatocarcinogenesis | 1-gen-2020 | Orrù, Claudia; Perra, Andrea; Kowalik, Marta Anna; Rizzolio, Sabrina; Puliga, Elisabetta; Cabras, Lavinia; Giordano, Silvia; Columbano, Amedeo | CANCERS | - |
| Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming | 1-gen-2020 | Kowalik, M. A.; Puliga, E.; Cabras, L.; Sulas, P.; Petrelli, A.; Perra, A.; Ledda-Columbano, G. M.; Morandi, A.; Merlin, S.; Orru, C.; Sanchez-Martin, C.; Fornari, F.; Gramantieri, L.; Parri, M.; Rasola, A.; Bellomo, S. E.; Sebastian, C.; Follenzi, A.; Giordano, S.; Columbano, A. | JOURNAL OF HEPATOLOGY | - |
| Design, synthesis and biological evaluation of novel TRβ selective agonists sustained by ADME-toxicity analysis | 1-gen-2020 | Runfola, M.; Sestito, S.; Bellusci, L.; La Pietra, V.; D'Amore, V. M.; Kowalik, M. A.; Chiellini, G.; Gul, S.; Perra, A.; Columbano, A.; Marinelli, L.; Novellino, E.; Rapposelli, S. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| THYROID HORMONE INHIBITS HEPATOCELLULAR CARCINOMA (HCC) DEVELOPMENT BY INTERFERING WITH THE METABOLIC PROFILE OF CANCER CELLS | 1-gen-2018 | Serra, Marina; Cabras, Lavinia; Kowalik, MARTA ANNA; Perra, Andrea; Sanchez-Martin, Carlos; Rasola, Andrea; Columbano, Amedeo | - | - |
| High frequency of β-catenin mutations in mouse hepatocellular carcinomas induced by a nongenotoxic constitutive androstane receptor agonist | 1-gen-2018 | Mattu, Sandra; Saliba, Christian; Sulas, Pia; Zavattari, Patrizia; Perra, Andrea; Kowalik, Marta A.; Monga, Satdarshan P.; Columbano, Amedeo | THE AMERICAN JOURNAL OF PATHOLOGY | - |
| Thyroid hormones, thyromimetics and their metabolites in the treatment of liver disease | 1-gen-2018 | Kowalik, Marta A.; Columbano, Amedeo; Perra, Andrea | FRONTIERS IN ENDOCRINOLOGY | - |
| Emerging role of the pentose phosphate pathway in hepatocellular carcinoma | 1-gen-2017 | Kowalik, Marta Anna; Columbano, Amedeo; Perra, Andrea | FRONTIERS IN ONCOLOGY | - |
| Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis | 1-gen-2016 | Kowalik, MARTA ANNA; Guzzo, Giulia; Morandi, Andrea; Perra, Andrea; Menegon, Silvia; Masgras, Ionica; Trevisan, Elena; Angioni, MARIA MADDALENA; Fornari, Francesca; Quagliata, Luca; Ledda, GIOVANNA MARIA; Gramantieri, Laura; Terracciano, Luigi; Giordano, Silvia; Chiarugi, Paola; Rasola, Andrea; Columbano, Amedeo | ONCOTARGET | - |
| Induction of autophagy promotes the growth of early preneoplastic rat liver nodules | 1-gen-2016 | Kowalik, MARTA ANNA; Perra, Andrea; Ledda, GIOVANNA MARIA; Ippolito, G; Piacentini, M; Columbano, Amedeo; Falasca, L. | ONCOTARGET | - |
| Statistical health monitoring applied to a metabolomic study of experimental hepatocarcinogenesis: an alternative approach to supervised methods for the identification of false positives | 1-gen-2016 | DEL CARRATORE, Francesco; Lussu, Milena; Kowalik, MARTA ANNA; Perra, Andrea; Griffin, Jl; Atzori, Luigi; Grosso, Massimiliano | ANALYTICAL CHEMISTRY | - |
| Global gene expression profile of normal and regenerating liver in young and old mice | 1-gen-2015 | Pibiri, Monica; Sulas, Pia; Leoni, VERA PIERA; Perra, Andrea; Kowalik, MARTA ANNA; Cordella, Angela; Saggese, Pasquale; Nassa, Giovanni; Ravo, Maria | AGE | - |
| Reply to: "YAP in tumorigenesis: Friend or foe?" | 1-gen-2015 | Perra, Andrea; Kowalik, MARTA ANNA; Giordano, S; Columbano, Amedeo | JOURNAL OF HEPATOLOGY | - |
| Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis | 1-gen-2015 | Zavattari, Patrizia; Perra, Andrea; Menegon, S; Kowalik, MARTA ANNA; Petrelli, A; Angioni, MARIA MADDALENA; Follenzi, A; Quagliata, L; Ledda, GIOVANNA MARIA; Terracciano, L; Giordano, S; Columbano, Amedeo | HEPATOLOGY | - |
| Cytokeratin-19 positivity is acquired along cancer progression and does not predict cell origin in rat hepatocarcinogenesis | 1-gen-2015 | Kowalik, MARTA ANNA; Sulas, Pia; Ledda, GIOVANNA MARIA; Giordano, S; Columbano, Amedeo; Perra, Andrea | ONCOTARGET | - |
| Local hypothyroidism favors the progression of preneoplastic lesions to hepatocellular carcinoma in rats | 1-gen-2015 | Frau, C; Loi, Roberto; Petrelli, A; Perra, Andrea; Menegon, S; Kowalik, MARTA ANNA; Pinna, S; Leoni, VERA PIERA; Fornari, F; Gramantieri, L; Ledda, GIOVANNA MARIA; Giordano, S; Columbano, Amedeo | HEPATOLOGY | - |
| YAP activation is an early event and a potential therapeutic target in liver cancer development | 1-gen-2014 | Perra, Andrea; Kowalik, Ma; Ghiso, E; Ledda, GIOVANNA MARIA; Di Tommaso, L; Angioni, MARIA MADDALENA; Raschioni, C; Testore, E; Roncalli, M; Giordano, S; Columbano, Amedeo | JOURNAL OF HEPATOLOGY | - |
| MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC). | 1-gen-2014 | Petrelli, A; Perra, Andrea; Cora, D; Sulas, P; Menegon, S; Manca, C; Migliore, C; Kowalik M., A; Ledda, GIOVANNA MARIA; Giordano, S; Columbano, Amedeo | HEPATOLOGY | - |
| Transcription profiling by array of mouse liver from TCPOBOP treated wild type and c-jun conditional knockout animals. | 1-gen-2012 | Leoni, Vp; Ledda, GIOVANNA MARIA; Pibiri, Monica; Saliba, C; Perra, Andrea; Kowalik, Ma; Grober Oli, Mv; Ravo, M; Weisz, A; Ghiso, E; Giordano, S; Columbano, A. | - | - |
| Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3 | 1-gen-2011 | Leoni, VERA PIERA; Ledda, GIOVANNA MARIA; Pibiri, Monica; Saliba, C; Perra, Andrea; Kowalik, MARTA ANNA; Grober, Om; Ravo, M; Weisz, A; Locker, J; Ghiso, E; Giordano, S; Columbano, Amedeo | JOURNAL OF HEPATOLOGY | - |
| Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice | 1-gen-2011 | Kowalik, MARTA ANNA; Saliba, C; Pibiri, Monica; Perra, Andrea; Ledda, GIOVANNA MARIA; Sarotto, I; Ghiso, E; Giordano, S; Columbano, Amedeo | HEPATOLOGY | - |
| Reply to: Clinical correlation of miR-375 and alpha-fetoprotein in hepatocellular carcinoma: comparison in mice and humans | 1-gen-2011 | Kowalik, MARTA ANNA; Ledda, GIOVANNA MARIA; Giordano, S; Columbano, Amedeo | HEPATOLOGY | - |
| Gender-specific interplay of signaling through β-catenin and CAR in the regulation of xenobiotic-induced hepatocyte proliferation | 1-gen-2011 | Braeuning, A; Heubach, Y; Knorpp, T; Kowalik, MARTA ANNA; Templin, M; Columbano, Amedeo; Schwarz, M. | TOXICOLOGICAL SCIENCES | - |
| TRbeta is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells | 1-gen-2010 | Kowalik, MARTA ANNA; Perra, Andrea; Pibiri, Monica; Cocco, Mt; Samarut, J; Plateroti, M; Ledda, GIOVANNA MARIA; Columbano, Amedeo | JOURNAL OF HEPATOLOGY | - |
| Effect of the ligands of thyroid hormone receptor on non-alcoholic fatty liver disease | 23-gen-2009 | - | - | Università degli Studi di Cagliari |
| Early metabolic changes in a liver carcinogenesis model | 1-gen-2009 | Atzori, Luigi; Weljie, Am; Kowalik, M; Perra, Andrea; Columbano, A; Griffin, Jl | - | - |
| Early Metabolic Changes in preneoplastc nodules of the liver | 1-gen-2009 | Weljie, ; Kowalik, M; Perra, Andrea; Columbano, A; Griffin, Jl; Atzori, Luigi | - | - |
| Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype | 1-gen-2009 | Perra, Andrea; Kowalik, MARTA ANNA; Pibiri, Monica; Ledda, GIOVANNA MARIA; Columbano, Amedeo | HEPATOLOGY | - |
| Characterization Of Early Stage Metabolic Perturbations In A Rat Model Of Hepatocellular Carcinogenesis | 1-gen-2008 | Weljie, A; Kowalik, M; Atzori, Luigi; Griffin, Jl | - | - |
| Thyroid hormone (T3) and TRbeta agonist GC-1 inhibit/reverse nonalcoholic fatty liver in rats | 1-gen-2008 | Perra, Andrea; Simbula, Gabriella; Simbula, M; Pibiri, Monica; Kowalik, MARTA ANNA; Sulas, P; Cocco, Mt; Ledda, GIOVANNA MARIA; Columbano, Amedeo | THE FASEB JOURNAL | - |
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