Università degli Studi di Cagliari
Valentina Onnis
Novel Anti-proliferative Agents
2024-01-01 Onnis, Valentina
Discovery of a New Class of 1-(4-Sulfamoylbenzoyl)piperidine-4-carboxamides as Human Carbonic Anhydrase Inhibitors
2024-01-01 Moi, Davide; Vittorio, Serena; Angeli, Andrea; Supuran, Claudiu T.; Onnis, Valentina
Exploring the Antiviral Potential of Esters of Cinnamic Acids with Quercetin
2024-01-01 Manca, Valeria; Chianese, Annalisa; Palmas, Vanessa; Etzi, Federica; Zannella, Carla; Moi, Davide; Secci, Francesco; Serreli, Gabriele; Sarais, Giorgia; Morone, Maria Vittoria; Galdiero, Massimiliano; Onnis, Valentina; Manzin, Aldo; Sanna, Giuseppina
Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors
2023-01-01 Moi, Davide; Vittorio, Serena; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Prokineticin System Is a Pharmacological Target to Counteract Pain and Its Comorbid Mood Alterations in an Osteoarthritis Murine Model
2023-01-01 Galimberti, Giulia; Amodeo, Giada; Magni, Giulia; Riboldi, Benedetta; Balboni, Gianfranco; Onnis, Valentina; Ceruti, Stefania; Sacerdote, Paola; Franchi, Silvia
Synthesis of Sulfonamides Incorporating Piperidinyl-Hydrazidoureido and Piperidinyl-Hydrazidothioureido Moieties and Their Carbonic Anhydrase I, II, IX and XII Inhibitory Activity
2023-01-01 Moi, Davide; Deplano, Alessandro; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Special Issue “Novel Anti-Proliferative Agents”
2023-01-01 Onnis, Valentina
Molecular Basis for Non-Covalent, Non-Competitive FAAH Inhibition
2022-01-01 Morgillo, Carmine Marco; Lupia, Antonio; Deplano, Alessandro; Pirone, Luciano; Fiorillo, Bianca; Pedone, Emilia; Luque, F. Javier; Onnis, Valentina; Moraca, Federica; Catalanotti, Bruno
Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets
2022-01-01 Madeddu, Silvia; Ibba, Roberta; Sanna, Giuseppina; Piras, Sandra; Riu, Federico; Marongiu, Alessandra; Ambrosino, Annalisa; Caria, Paola; Onnis, Valentina; Franci, Gianluigi; Manzin, Aldo; Carta, Antonio
Synthesis and Antiproliferative Effect of Halogenated Coumarin Derivatives
2022-01-01 Dettori, Tinuccia; Sanna, Giuseppina; Cocco, Andrea; Serreli, Gabriele; Deiana, Monica; Palmas, Vanessa; Onnis, Valentina; Pilia, Luca; Melis, Nicola; Moi, Davide; Caria, Paola; Secci, Francesco
Cholinium-Based Ionic Liquids from Hydroxycinnamic Acids as New Promising Bioactive Agents: A Combined Experimental and Theoretical Investigation
2021-01-01 Demurtas, Monica; Onnis, Valentina; Zucca, Paolo; Rescigno, Antonio; Lachowicz, Joanna Izabela; De Villiers Engelbrecht, Leon; Nieddu, Mariella; Ennas, Guido; Scano, Alessandra; Mocci, Francesca; Cesare Marincola, Flaminia
Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors
2021-01-01 Angeli, Andrea; Carta, Fabrizio; Nocentini, Alessio; Winum, Jean-Yves; Zalubovskis, Raivis; Onnis, Valentina; Eldehna, Wagdy M; Capasso, Clemente; Carradori, Simone; Donald, William A; Dedhar, Shoukat; Supuran, Claudiu T
Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents
2021-01-01 Deplano, Alessandro; Karlsson, Jessica; Moraca, Federica; Svensson, Mona; Cristiano, Claudia; Morgillo, Carmine Marco; Fowler, Christopher J.; Russo, Roberto; Catalanotti, Bruno; Onnis, Valentina
Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents
2020-01-01 Oliva, Paola; Onnis, Valentina; Balboni, Elisa; Hamel, Ernest; Estévez-Sarmiento, Francisco; Quintana, José; Estévez, Francisco; Brancale, Andrea; Ferla, Salvatore; Manfredini, Stefano; Romagnoli, Romeo
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles
2020-01-01 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication
2020-01-01 Corona, Angela; Onnis, Valentina; Del Vecchio, Claudia; Esposito, Francesca; Cheng, Yung-Chi; Tramontano, Enzo
In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives
2020-01-01 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
Ruthenium(II) Complexes of Isothiazole Ligands: Crystal Structure, HSA/DNA Interactions, Cytotoxic Activity and Molecular Docking Simulations
2020-01-01 Djukić, Maja B.; Jeremić, Marija S.; Filipović, Ignjat P.; Klisurić, Olivera R.; Jelić, Ratomir M.; Popović, Suzana; Matić, Sanja; Onnis, Valentina; Matović, Zoran D.
Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment
2020-01-01 Angeli, Andrea; Carta, Fabrizio; Nocentini, Alessio; Winum, Jean-Yves; Zalubovskis, Raivis; Akdemir, Atilla; Onnis, Valentina; Eldehna, Wagdy M.; Capasso, Clemente; Simone, Giuseppina De; Monti, Simona Maria; Carradori, Simone; Donald, William A.; Dedhar, Shoukat; Supuran, Claudiu T.
Synthesis, characterization, HSA/DNA interactions and antitumor activity of new [Ru(η6-p-cymene)Cl2(L)] complexes
2020-01-01 Đukić, Maja B.; Jeremić, Marija S.; Filipović, Ignjat P.; Klisurić, Olivera R.; Kojić, Vesna V.; Jakimov, Dimitar S.; Jelić, Ratomir M.; Onnis, Valentina; Matović, Zoran D.
Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen
2020-01-01 Deplano, Alessandro; Karlsson, Jessica; Svensson, Mona; Moraca, Federica; Catalanotti, Bruno; Fowler, Christopher J.; Onnis, Valentina
Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors
2020-01-01 Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Piras, Valentina; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors
2020-01-01 Nocentini, Alessio; Moi, Davide; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
The fatty acid amide hydrolase and cyclooxygenase-inhibitory properties of novel amide derivatives of carprofen
2020-01-01 Deplano, Alessandro; Karlsson, Jessica; Fowler, Christopher J.; Onnis, Valentina
Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors
2019-01-01 Moi, Davide; Foster, Paul A.; Rimmer, Lucy G.; Jaffri, Alisha; Deplano, Alessandro; Balboni, Gianfranco; Onnis, Valentina; Potter, Barry V. L.
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones
2019-01-01 Demurtas, Monica; Baldisserotto, Anna; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors
2019-01-01 Deplano, Alessandro; Cipriano, Mariateresa; Moraca, Federica; Novellino, Ettore; Catalanotti, Bruno; Fowler, Christopher J.; Onnis, Valentina
Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation
2019-01-01 Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina
Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy
2019-01-01 Moschetti, Giorgia; Amodeo, Giada; Maftei, Daniela; Lattanzi, Roberta; Procacci, Patrizia; Sartori, Patrizia; Balboni, Gianfranco; Onnis, Valentina; Conte, Vincenzo; Panerai, Alberto; Sacerdote, Paola; Franchi, Silvia
Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors
2018-01-01 Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Onnis, Valentina; Supuran, Claudiu T.
Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy
2018-01-01 Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Salvadori, Severo; Onnis, Valentina; Supuran, Claudiu T.
Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity
2018-01-01 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina
Novel propanamides as fatty acid amide hydrolase inhibitors
2017-01-01 Deplano, Alessandro; Morgillo, Carmine Marco; Demurtas, Monica; Björklund, Emmelie; Cipriano, Mariateresa; Svensson, Mona; Hashemian, Sanaz; Smaldone, Giovanni; Pedone, Emilia; Luque, F. Javier; Cabiddu, MARIA GRAZIA; Novellino, Ettore; Fowler, Christopher J.; Catalanotti, Bruno; Onnis, Valentina
3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes
2017-01-01 Park, Byeongyeon; Nam, Ji Hye; Kim, Jin Han; Kim, Hyoung Ja; Onnis, Valentina; Balboni, Gianfranco; Lee, Kyung Tae; Park, Jeong Ho; Catto, Marco; Carotti, Angelo; Lee, Jae Yeol
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions
2017-01-01 Corona, Angela; Onnis, Valentina; Deplano, Alessandro; Bianco, Giulia; Demurtas, Monica; Distinto, Simona; Cheng, Yung Chi; Alcaro, Stefano; Esposito, Francesca; Tramontano, Enzo
Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo
2017-01-01 Traboulsi, Wael; Sergent, Frederic; Boufettal, Houssine; Brouillet, Sophie; Slim, Rima; Hoffmann, Pascale; Benlahfid, Mohammed; Zhou, qun yong; Balboni, Gianfranco; Onnis, Valentina; Bolze, Pierre Adrien; Salomon, Aude; Sauthier, Philippe; Mallet, François; Aboussaouira, Touria; Feige, Jean Jacques; Benharouga, Mohamed; Alfaidy, Nadia
Haloacetophenones as newly potent nematicides against Meloidogyne incognita
2017-01-01 Tocco, Graziella; Eloh, Kodjo; Onnis, Valentina; Sasanelli, Nicola; Caboni, Pierluigi
Potent nematicidal activity of maleimide derivatives on Meloidogyne incognita
2016-01-01 Eloh, Kodjo; Demurtas, Monica; Mura, MANUEL GIACOMO; Deplano, Alessandro; Onnis, Valentina; Sasanelli, N; Maxia, Andrea; Caboni, Pierluigi
Antagonism of the prokineticin system prevents and reverses allodynia and inflammation in a mouse model of diabetes
2016-01-01 Castelli, M; Amodeo, G; Negri, L; Lattanzi, R; Maftei, D; Gotti, C; Pistillo, F; Onnis, Valentina; Congiu, Cenzo; Panerai, Ae; Sacerdote, P; Franchi, S.
Effect of the T-type channel blocker KYS-05090S in mouse models of acute and neuropathic pain
2016-01-01 M'Dahoma, Saïd; Gadotti, Vinicius M; Zhang, Fang Xiong; Park, Byeongyeon; Nam, Ji Hye; Onnis, Valentina; Balboni, Gianfranco; Lee, Jae Yeol; Zamponi, Gerald W.
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones
2016-01-01 Onnis, Valentina; Demurtas, Monica; Deplano, Alessandro; Balboni, Gianfranco; Baldisserotto, A; Manfredini, S; Pacifico, S; Liekens, S; Balzarini, J.
Nematicidal activity of acetophenones and chalcones against Meloidogyne incognita and structure-activity considerations
2016-01-01 Caboni, Pierluigi; Aissani, Nadhem; Demurtas, Monica; Ntalli, Nikoletta; Onnis, Valentina
Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives
2015-01-01 Sakakibara, Norikazu; Balboni, Gianfranco; Congiu, Cenzo; Onnis, Valentina; Demizu, Yosuke; Misawa, Takashi; Kurihara, Masaaki; Kato, Yoshihisa; Maruyama, Tokumi; Toyama, Masaaki; Okamoto, Mika; Baba, Masanori
In vitro nematicidal activity of aryl hydrazones and comparative GC-MS metabolomics analysis
2015-01-01 Eloh, Kodjo; Demurtas, Monica; Deplano, Alessandro; Ngoutane Mfopa, A; Murgia, Antonio; Maxia, Andrea; Onnis, Valentina; Caboni, Pierluigi
TRPV1 modulators: synthesis and in vitro evaluation of 1-heteroarylpiperidinecarboxamide and piperazinylurea derivatives
2015-01-01 Congiu, Cenzo; Onnis, Valentina; Balboni, Gianfranco; Schiano Moriello, A; Di Marzo, V; De Petrocellis, L.
PPAR controls pregnancy outcome through activation of EG-VEGF: new insights into the mechanism of placental development
2015-01-01 Vanessa, Garnier; Wael, Traboulsi; Aude, Salomon; Sophie, Brouillet; Thierry, Fournier; Carine, Winkler; Beatrice, Desvergne; Pascale, Hoffmann; Qun Yong, Zhou; Congiu, Cenzo; Onnis, Valentina; Mohamed, Benharouga; Jean Jacques, Feige; Nadia, Alfaidy
Critical role for prokineticin 2 in CNS autoimmunity
2015-01-01 ABOU HAMDAN, M; Costanza, M; Fontana, E; DI DARIO, M; Musio, S; Congiu, Cenzo; Onnis, Valentina; Lattanzi, R; Radaelli, M; Martinelli, V; Salvadori, S; Negri, L; Poliani, Pl; Farina, C; Balboni, Gianfranco; Steinman, L; Pedotti, R.
Interaction of the N-(3-Methylpyridin-2-yl)amide derivatives of flurbiprofen and ibuprofen with FAAH: Enantiomeric selectivity and binding mode
2015-01-01 Karlsson, Jessica; Morgillo, Carmine M; Deplano, Alessandro; Smaldone, Giovanni; Pedone, Emilia; Luque, F. Javier; Svensson, Mona; Novellino, Ettore; Congiu, Cenzo; Onnis, Valentina; Catalanotti, Bruno; Fowler, Christopher J.
Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties
2015-01-01 Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Balboni, Gianfranco; Ceruso, Mariangela; Supuran, Claudiu T.
Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor
2015-01-01 Gouveia Figueira, S; Karlsson, J; Deplano, Alessandro; Hashemian, S; Svensson, M; Fredriksson Sundbom, M; Congiu, Cenzo; Onnis, Valentina; Fowler, Cj
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Novel Anti-proliferative Agents | 1-gen-2024 | Onnis, Valentina | - | MDPI |
| Discovery of a New Class of 1-(4-Sulfamoylbenzoyl)piperidine-4-carboxamides as Human Carbonic Anhydrase Inhibitors | 1-gen-2024 | Moi, Davide; Vittorio, Serena; Angeli, Andrea; Supuran, Claudiu T.; Onnis, Valentina | ACS MEDICINAL CHEMISTRY LETTERS | - |
| Exploring the Antiviral Potential of Esters of Cinnamic Acids with Quercetin | 1-gen-2024 | Manca, Valeria; Chianese, Annalisa; Palmas, Vanessa; Etzi, Federica; Zannella, Carla; Moi, Davide; Secci, Francesco; Serreli, Gabriele; Sarais, Giorgia; Morone, Maria Vittoria; Galdiero, Massimiliano; Onnis, Valentina; Manzin, Aldo; Sanna, Giuseppina | VIRUSES | - |
| Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors | 1-gen-2023 | Moi, Davide; Vittorio, Serena; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | MOLECULES | - |
| Prokineticin System Is a Pharmacological Target to Counteract Pain and Its Comorbid Mood Alterations in an Osteoarthritis Murine Model | 1-gen-2023 | Galimberti, Giulia; Amodeo, Giada; Magni, Giulia; Riboldi, Benedetta; Balboni, Gianfranco; Onnis, Valentina; Ceruti, Stefania; Sacerdote, Paola; Franchi, Silvia | CELLS | - |
| Synthesis of Sulfonamides Incorporating Piperidinyl-Hydrazidoureido and Piperidinyl-Hydrazidothioureido Moieties and Their Carbonic Anhydrase I, II, IX and XII Inhibitory Activity | 1-gen-2023 | Moi, Davide; Deplano, Alessandro; Angeli, Andrea; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | MOLECULES | - |
| Special Issue “Novel Anti-Proliferative Agents” | 1-gen-2023 | Onnis, Valentina | PHARMACEUTICALS | - |
| Molecular Basis for Non-Covalent, Non-Competitive FAAH Inhibition | 1-gen-2022 | Morgillo, Carmine Marco; Lupia, Antonio; Deplano, Alessandro; Pirone, Luciano; Fiorillo, Bianca; Pedone, Emilia; Luque, F. Javier; Onnis, Valentina; Moraca, Federica; Catalanotti, Bruno | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Human Enterovirus B: Selective Inhibition by Quinoxaline Derivatives and Bioinformatic RNA-Motif Identification as New Targets | 1-gen-2022 | Madeddu, Silvia; Ibba, Roberta; Sanna, Giuseppina; Piras, Sandra; Riu, Federico; Marongiu, Alessandra; Ambrosino, Annalisa; Caria, Paola; Onnis, Valentina; Franci, Gianluigi; Manzin, Aldo; Carta, Antonio | PHARMACEUTICALS | - |
| Synthesis and Antiproliferative Effect of Halogenated Coumarin Derivatives | 1-gen-2022 | Dettori, Tinuccia; Sanna, Giuseppina; Cocco, Andrea; Serreli, Gabriele; Deiana, Monica; Palmas, Vanessa; Onnis, Valentina; Pilia, Luca; Melis, Nicola; Moi, Davide; Caria, Paola; Secci, Francesco | MOLECULES | - |
| Cholinium-Based Ionic Liquids from Hydroxycinnamic Acids as New Promising Bioactive Agents: A Combined Experimental and Theoretical Investigation | 1-gen-2021 | Demurtas, Monica; Onnis, Valentina; Zucca, Paolo; Rescigno, Antonio; Lachowicz, Joanna Izabela; De Villiers Engelbrecht, Leon; Nieddu, Mariella; Ennas, Guido; Scano, Alessandra; Mocci, Francesca; Cesare Marincola, Flaminia | ACS SUSTAINABLE CHEMISTRY & ENGINEERING | - |
| Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors | 1-gen-2021 | Angeli, Andrea; Carta, Fabrizio; Nocentini, Alessio; Winum, Jean-Yves; Zalubovskis, Raivis; Onnis, Valentina; Eldehna, Wagdy M; Capasso, Clemente; Carradori, Simone; Donald, William A; Dedhar, Shoukat; Supuran, Claudiu T | BIOPHYSICAL JOURNAL | - |
| Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents | 1-gen-2021 | Deplano, Alessandro; Karlsson, Jessica; Moraca, Federica; Svensson, Mona; Cristiano, Claudia; Morgillo, Carmine Marco; Fowler, Christopher J.; Russo, Roberto; Catalanotti, Bruno; Onnis, Valentina | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents | 1-gen-2020 | Oliva, Paola; Onnis, Valentina; Balboni, Elisa; Hamel, Ernest; Estévez-Sarmiento, Francisco; Quintana, José; Estévez, Francisco; Brancale, Andrea; Ferla, Salvatore; Manfredini, Stefano; Romagnoli, Romeo | MOLECULES | - |
| Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles | 1-gen-2020 | Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| 2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication | 1-gen-2020 | Corona, Angela; Onnis, Valentina; Del Vecchio, Claudia; Esposito, Francesca; Cheng, Yung-Chi; Tramontano, Enzo | MOLECULES | - |
| In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives | 1-gen-2020 | Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni, Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | PHARMACEUTICALS | - |
| Ruthenium(II) Complexes of Isothiazole Ligands: Crystal Structure, HSA/DNA Interactions, Cytotoxic Activity and Molecular Docking Simulations | 1-gen-2020 | Djukić, Maja B.; Jeremić, Marija S.; Filipović, Ignjat P.; Klisurić, Olivera R.; Jelić, Ratomir M.; Popović, Suzana; Matić, Sanja; Onnis, Valentina; Matović, Zoran D. | CHEMISTRYSELECT | - |
| Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment | 1-gen-2020 | Angeli, Andrea; Carta, Fabrizio; Nocentini, Alessio; Winum, Jean-Yves; Zalubovskis, Raivis; Akdemir, Atilla; Onnis, Valentina; Eldehna, Wagdy M.; Capasso, Clemente; Simone, Giuseppina De; Monti, Simona Maria; Carradori, Simone; Donald, William A.; Dedhar, Shoukat; Supuran, Claudiu T. | METABOLITES | - |
| Synthesis, characterization, HSA/DNA interactions and antitumor activity of new [Ru(η6-p-cymene)Cl2(L)] complexes | 1-gen-2020 | Đukić, Maja B.; Jeremić, Marija S.; Filipović, Ignjat P.; Klisurić, Olivera R.; Kojić, Vesna V.; Jakimov, Dimitar S.; Jelić, Ratomir M.; Onnis, Valentina; Matović, Zoran D. | JOURNAL OF INORGANIC BIOCHEMISTRY | - |
| Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen | 1-gen-2020 | Deplano, Alessandro; Karlsson, Jessica; Svensson, Mona; Moraca, Federica; Catalanotti, Bruno; Fowler, Christopher J.; Onnis, Valentina | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors | 1-gen-2020 | Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Piras, Valentina; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors | 1-gen-2020 | Nocentini, Alessio; Moi, Davide; Deplano, Alessandro; Osman, Sameh M.; Alothman, Zeid A.; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| The fatty acid amide hydrolase and cyclooxygenase-inhibitory properties of novel amide derivatives of carprofen | 1-gen-2020 | Deplano, Alessandro; Karlsson, Jessica; Fowler, Christopher J.; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors | 1-gen-2019 | Moi, Davide; Foster, Paul A.; Rimmer, Lucy G.; Jaffri, Alisha; Deplano, Alessandro; Balboni, Gianfranco; Onnis, Valentina; Potter, Barry V. L. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones | 1-gen-2019 | Demurtas, Monica; Baldisserotto, Anna; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | BIOORGANIC CHEMISTRY | - |
| Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors | 1-gen-2019 | Deplano, Alessandro; Cipriano, Mariateresa; Moraca, Federica; Novellino, Ettore; Catalanotti, Bruno; Fowler, Christopher J.; Onnis, Valentina | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation | 1-gen-2019 | Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy | 1-gen-2019 | Moschetti, Giorgia; Amodeo, Giada; Maftei, Daniela; Lattanzi, Roberta; Procacci, Patrizia; Sartori, Patrizia; Balboni, Gianfranco; Onnis, Valentina; Conte, Vincenzo; Panerai, Alberto; Sacerdote, Paola; Franchi, Silvia | JOURNAL OF NEUROINFLAMMATION | - |
| Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors | 1-gen-2018 | Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Onnis, Valentina; Supuran, Claudiu T. | BIOORGANIC CHEMISTRY | - |
| Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy | 1-gen-2018 | Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Salvadori, Severo; Onnis, Valentina; Supuran, Claudiu T. | BIOORGANIC CHEMISTRY | - |
| Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity | 1-gen-2018 | Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Novel propanamides as fatty acid amide hydrolase inhibitors | 1-gen-2017 | Deplano, Alessandro; Morgillo, Carmine Marco; Demurtas, Monica; Björklund, Emmelie; Cipriano, Mariateresa; Svensson, Mona; Hashemian, Sanaz; Smaldone, Giovanni; Pedone, Emilia; Luque, F. Javier; Cabiddu, MARIA GRAZIA; Novellino, Ettore; Fowler, Christopher J.; Catalanotti, Bruno; Onnis, Valentina | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| 3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes | 1-gen-2017 | Park, Byeongyeon; Nam, Ji Hye; Kim, Jin Han; Kim, Hyoung Ja; Onnis, Valentina; Balboni, Gianfranco; Lee, Kyung Tae; Park, Jeong Ho; Catto, Marco; Carotti, Angelo; Lee, Jae Yeol | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | Elsevier Ltd |
| Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions | 1-gen-2017 | Corona, Angela; Onnis, Valentina; Deplano, Alessandro; Bianco, Giulia; Demurtas, Monica; Distinto, Simona; Cheng, Yung Chi; Alcaro, Stefano; Esposito, Francesca; Tramontano, Enzo | PATHOGENS AND DISEASE | - |
| Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo | 1-gen-2017 | Traboulsi, Wael; Sergent, Frederic; Boufettal, Houssine; Brouillet, Sophie; Slim, Rima; Hoffmann, Pascale; Benlahfid, Mohammed; Zhou, qun yong; Balboni, Gianfranco; Onnis, Valentina; Bolze, Pierre Adrien; Salomon, Aude; Sauthier, Philippe; Mallet, François; Aboussaouira, Touria; Feige, Jean Jacques; Benharouga, Mohamed; Alfaidy, Nadia | CLINICAL CANCER RESEARCH | - |
| Haloacetophenones as newly potent nematicides against Meloidogyne incognita | 1-gen-2017 | Tocco, Graziella; Eloh, Kodjo; Onnis, Valentina; Sasanelli, Nicola; Caboni, Pierluigi | INDUSTRIAL CROPS AND PRODUCTS | - |
| Potent nematicidal activity of maleimide derivatives on Meloidogyne incognita | 1-gen-2016 | Eloh, Kodjo; Demurtas, Monica; Mura, MANUEL GIACOMO; Deplano, Alessandro; Onnis, Valentina; Sasanelli, N; Maxia, Andrea; Caboni, Pierluigi | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | - |
| Antagonism of the prokineticin system prevents and reverses allodynia and inflammation in a mouse model of diabetes | 1-gen-2016 | Castelli, M; Amodeo, G; Negri, L; Lattanzi, R; Maftei, D; Gotti, C; Pistillo, F; Onnis, Valentina; Congiu, Cenzo; Panerai, Ae; Sacerdote, P; Franchi, S. | PLOS ONE | - |
| Effect of the T-type channel blocker KYS-05090S in mouse models of acute and neuropathic pain | 1-gen-2016 | M'Dahoma, Saïd; Gadotti, Vinicius M; Zhang, Fang Xiong; Park, Byeongyeon; Nam, Ji Hye; Onnis, Valentina; Balboni, Gianfranco; Lee, Jae Yeol; Zamponi, Gerald W. | PFLÜGERS ARCHIV | - |
| Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones | 1-gen-2016 | Onnis, Valentina; Demurtas, Monica; Deplano, Alessandro; Balboni, Gianfranco; Baldisserotto, A; Manfredini, S; Pacifico, S; Liekens, S; Balzarini, J. | MOLECULES | - |
| Nematicidal activity of acetophenones and chalcones against Meloidogyne incognita and structure-activity considerations | 1-gen-2016 | Caboni, Pierluigi; Aissani, Nadhem; Demurtas, Monica; Ntalli, Nikoletta; Onnis, Valentina | PEST MANAGEMENT SCIENCE | - |
| Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives | 1-gen-2015 | Sakakibara, Norikazu; Balboni, Gianfranco; Congiu, Cenzo; Onnis, Valentina; Demizu, Yosuke; Misawa, Takashi; Kurihara, Masaaki; Kato, Yoshihisa; Maruyama, Tokumi; Toyama, Masaaki; Okamoto, Mika; Baba, Masanori | ANTIVIRAL CHEMISTRY & CHEMOTHERAPY | - |
| In vitro nematicidal activity of aryl hydrazones and comparative GC-MS metabolomics analysis | 1-gen-2015 | Eloh, Kodjo; Demurtas, Monica; Deplano, Alessandro; Ngoutane Mfopa, A; Murgia, Antonio; Maxia, Andrea; Onnis, Valentina; Caboni, Pierluigi | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | - |
| TRPV1 modulators: synthesis and in vitro evaluation of 1-heteroarylpiperidinecarboxamide and piperazinylurea derivatives | 1-gen-2015 | Congiu, Cenzo; Onnis, Valentina; Balboni, Gianfranco; Schiano Moriello, A; Di Marzo, V; De Petrocellis, L. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| PPAR controls pregnancy outcome through activation of EG-VEGF: new insights into the mechanism of placental development | 1-gen-2015 | Vanessa, Garnier; Wael, Traboulsi; Aude, Salomon; Sophie, Brouillet; Thierry, Fournier; Carine, Winkler; Beatrice, Desvergne; Pascale, Hoffmann; Qun Yong, Zhou; Congiu, Cenzo; Onnis, Valentina; Mohamed, Benharouga; Jean Jacques, Feige; Nadia, Alfaidy | AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM | - |
| Critical role for prokineticin 2 in CNS autoimmunity | 1-gen-2015 | ABOU HAMDAN, M; Costanza, M; Fontana, E; DI DARIO, M; Musio, S; Congiu, Cenzo; Onnis, Valentina; Lattanzi, R; Radaelli, M; Martinelli, V; Salvadori, S; Negri, L; Poliani, Pl; Farina, C; Balboni, Gianfranco; Steinman, L; Pedotti, R. | NEUROLOGY® NEUROIMMUNOLOGY & NEUROINFLAMMATION | - |
| Interaction of the N-(3-Methylpyridin-2-yl)amide derivatives of flurbiprofen and ibuprofen with FAAH: Enantiomeric selectivity and binding mode | 1-gen-2015 | Karlsson, Jessica; Morgillo, Carmine M; Deplano, Alessandro; Smaldone, Giovanni; Pedone, Emilia; Luque, F. Javier; Svensson, Mona; Novellino, Ettore; Congiu, Cenzo; Onnis, Valentina; Catalanotti, Bruno; Fowler, Christopher J. | PLOS ONE | - |
| Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties | 1-gen-2015 | Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Balboni, Gianfranco; Ceruso, Mariangela; Supuran, Claudiu T. | BIOORGANIC & MEDICINAL CHEMISTRY | - |
| Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor | 1-gen-2015 | Gouveia Figueira, S; Karlsson, J; Deplano, Alessandro; Hashemian, S; Svensson, M; Fredriksson Sundbom, M; Congiu, Cenzo; Onnis, Valentina; Fowler, Cj | PLOS ONE | - |
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