Università degli Studi di Cagliari
Alessandro De Logu
Improving the physical chemical properties of a very promising class of pyrrole antimycobacterial agents
In corso di stampa Poce, G; Alfonso, S; Cocozza, M; Porretta, Gc; Ballell, L; Bates, Rh; DE LOGU, Alessandro; Agus, E; De Rossi, E; Franzblau, Sg; Botta, M; Biava, M.
Synthesis, Biological Evaluation and Computational Studies of New Hydrazide Derivatives Containing 1,3,4-Oxadiazole as Antitubercular Agents
2022-01-01 Zampieri, D.; Fortuna, S.; Romano, M.; De Logu, A.; Cabiddu, G.; Sanna, A.; Mamolo, M. G.
Nano-Based Drug Delivery Systems of Potent MmpL3 Inhibitors for Tuberculosis Treatment
2022-01-01 Hanieh, P. N.; Consalvi, S.; Forte, J.; Cabiddu, G.; De Logu, A.; Poce, G.; Rinaldi, F.; Biava, M.; Carafa, M.; Marianecci, C.
Saggi e Dosaggi Microbiologici della Farmacopea. In Microbiologia Farmaceutica III Ed. Cap. 27
2021-01-01 De Logu, A.
Stafilococchi. In Microbiologia Farmaceutica. N. Carlone, R. Pompei, V. Tullio
2021-01-01 De Logu, A
6-Fluorophenylbenzohydrazides inhibit Mycobacterium tuberculosis growth through alteration of tryptophan biosynthesis
2021-01-01 Consalvi, S.; Venditti, G.; Zhu, J.; Boshoff, H. I.; Arora, K.; De Logu, A.; Ioerger, T. R.; Rubin, E. J.; Biava, M.; Poce, G.
Aspetti Microbiologici della Produzione Farmaceutica
2021-01-01 DE LOGU, Alessandro
Design, synthesis and antimycobacterial activity of benzoxazinone derivatives and open-ring analogues: Preliminary data and computational analysis
2019-01-01 Zampieri, D.; Mamolo, M. G.; Filingeri, J.; Fortuna, S.; De Logu, A.; Sanna, A.; Zanon, D.
Imidazole and 1,2,4-triazole-based derivatives gifted with antitubercular activity: Cytotoxicity and computational assessment
2019-01-01 Zampieri, Daniele; Cateni, Francesca; Moneghini, Mariarosa; Zacchigna, Marina; Laurini, Erik; Marson, Domenico; De Logu, Alessandro; Sanna, Adriana; Mamolo, Maria G
Novel Pyrazole-Containing Compounds Active against Mycobacterium tuberculosis
2019-01-01 Poce, G.; Consalvi, S.; Venditti, G.; Alfonso, S.; Desideri, N.; Fernandez-Menendez, R.; Bates, R. H.; Ballell, L.; Barros Aguirre, D.; Rullas, J.; De Logu, A.; Gardner, M.; Ioerger, T. R.; Rubin, E. J.; Biava, M.
Naturally occurring Diels-Alder-type adducts from Morus nigra as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B
2018-01-01 Mascarello, Alessandra; Orbem Menegatti, Angela Camila; Calcaterra, Andrea; Martins, Priscila Graziela Alves; Chiaradia-Delatorre, Louise Domeneghini; D'Acquarica, Ilaria; Ferrari, Franco; Pau, Valentina; Sanna, Adriana; De Logu, Alessandro; Botta, Maurizio; Botta, Bruno; Terenzi, Hernã¡n; Mori, Mattia
Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1
2018-01-01 Mori, Mattia; Deodato, Davide; Kasula, Mohan; Ferraris, Davide M; Sanna, Adriana; De Logu, Alessandro; Rizzi, Menico; Botta, Maurizio
In vivo potent BM635 analogue with improved drug-like properties
2018-01-01 Poce, Giovanna; Cocozza, Martina; Alfonso, Salvatore; Consalvi, Sara; Venditti, Giulia; Fernandez-Menendez, Raquel; Bates, Robert H; Barros Aguirre, David; Ballell, Lluis; De Logu, Alessandro; Vistoli, Giulio; Biava, Mariangela
Sherris. Microbiologia medica
2017-01-01 DE LOGU, Alessandro; Batoni, Giovanna; Caputo, Antonella; Ceccherini Nelli, Luca; Cenci, Elio; Cocuzza, Clementina; Maria Cuffini, Anna; D'Agostini, Cartesio; Di Francesco, Paolo; Di Luca, Dario; Fadda, Daniela; Favalli, Cartesio; Galdiero, Marilena; Galdiero, Massimiliano; Gariglio, Marisa; Gaziano, Roberta; Giammanco, Anna; Grelli, Sandro; Landolfo, Santo; Massidda, Orietta; Mastromarino, Paola; Mattina, Roberto; Miragliotta, Giuseppe; Pagani, Laura; Palù, Giorgio; Perito, Stefano; Salvatore, Paola; Sanguinetti, Maurizio; Serra, Corrado; Sessa, Rosa; Sinibaldi Vallebona, Paola; Stefani, Stefania; Valenti, Piera
Antimycobacterial Activiy of New 1,4-Benzoxazine-2-one derivatives and its 2-(arylamino)-4-oxobut-2-enoate, ring-open analogues
2017-01-01 Daniele, Zampieri; Marco, Bernecich; Maria Grazia, Mamolo; Sanna, Adriana; DE LOGU, Alessandro
Nuove strategie per lo sviluppo di farmaci antitubercolari: caratterizzazione di target alternativi e di fattori di virulenza in Mycobacterium tuberculosis
2016-01-01 DE LOGU, Alessandro
Discovery of in vitro antitubercular agents through in silico ligand-based approaches
2016-01-01 De Vita, D; Pandolfi, F; Cirilli, R; Scipione, L; Di Santo, R; Friggeri, L; Mori, M; Fiorucci, D; Maccari, G; Christopher, Rsa; Zamperini, C; Pau, V; DE LOGU, Alessandro; Tortorella, S; Botta, M.
Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida
2016-01-01 Meleddu, Rita; Distinto, Simona; Corona, Angela; Maccioni, Elias; Arridu, Antonella; Melis, Claudia; Bianco, Giulia; Matyus, Peter; Cottiglia, Filippo; Sanna, Adriana; DE LOGU, Alessandro
Antimycobacterial activity of new N1-[1-[1-aryl-3-[4-(1H-imidazol-1-yl)phenyl]-3-oxo]propyl]-pyridine-2-carboxamidrazone derivatives
2016-01-01 Zampieri, Daniele; Mamolo, Maria Grazia; Vio, Luciano; Romano, Maurizio; Skoko, Nataša; Baralle, Marco; Pau, Valentina; DE LOGU, Alessandro
Limonoids from Melia azedarach fruits as inhibitors of flaviviruses and mycobacterium tubercolosis
2015-01-01 Sanna, Giuseppina; Madeddu, Silvia; Giliberti, Gabriele; Ntalli, Nikoletta G.; Cottiglia, Filippo; DE LOGU, Alessandro; Agus, Emanuela; Caboni, Pierluigi
HPLC-DAD-MS analysis and antiviral activity of different extracts and isolated costituents from Bituminaria bituminosa
2014-01-01 Noccioli, C; Bertoli, A; Agus, E; DE LOGU, Alessandro; Pistelli, L.
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection
2013-01-01 Poce, G; Bates, Rh; Alfonso, S; Cocozza, M; Porretta, Gc; Ballell, L; Rullas, J; Ortega, F; DE LOGU, Alessandro; Agus, E; LA ROSA, Valentina; Pasca, Mr; De Rossi, E; Wae, B; Franzblau, Sg; Manetti, F; Botta, M; Biava, M.
2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents
2013-01-01 Arridu, A.; Meleddu, R.; Bianco, Giulia; Distinto, Simona; DE LOGU, Alessandro; Matyus, P.; Maccioni, Elias
Stafilococchi
2012-01-01 DE LOGU, Alessandro
Saggi e dosaggi microbiologici della Farmacopea
2012-01-01 DE LOGU, Alessandro
Aspetti microbiologici della produzione farmaceutica
2012-01-01 DE LOGU, Alessandro
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212
2012-01-01 LA ROSA, Valentina; Poce, G; ORTIZ CANSECO, J; Buroni, S; Pasca, Mr; Biava, M; Raju, Rm; Poretta, Gc; Alfons, S; Battilocchio, C; Javid, B; Sorrentino, F; Ioerger, Tr; Sacchettini, Jc; Manetti, F; Botta, M.; DE LOGU, Alessandro; Rubin, Ej; DE ROSSI, E.
Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases
2011-01-01 Casu, Laura; Cottiglia, Filippo; Leonti, Marco; DE LOGU, Alessandro; Agus, E; Tse Dinh, Yc; Lombardo, V; Sissi, C.
The MmpL3 protein is responsible for resistance to BM212, a lead antitubercular drug
2011-01-01 Canseco, Jo; LA ROSA, Valentina; Luhaj, A; Battaglia, S; Buroni, S; Biava, M; DE LOGU, Alessandro; Manetti, F; Botta, M; De Rossi, E.
Developing pyrrole-derived antimycobacterial agents: a rational lead optimization approach
2011-01-01 Biava, M; Porretta, Gc; Poce, G; Battilocchio, C; Alfonso, S; DE LOGU, Alessandro; Manetti, F; Botta, M.
Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin
2010-01-01 Biava, M; Porretta, Gc; Poce, G; Battilocchio, C; Alfonso, S; DE LOGU, Alessandro; Serra, N; Manetti, F; Botta, M.
Design, synthesis and microbiological characterization of 1,5-diphenyl and 1,5-diaryl-2-ethylpyrrole derivatives as new potential agents of infections sustained by MDR and XDR Mycobacterium tuberculosis.
2010-01-01 Agus, E; Biava, M; Porretta, Gc; Poce, G; Serra, N; Sanna, A; De Rossi, E; Piras, Cc; Manetti, F; Botta, M; DE LOGU, Alessandro
New pyrrole derivatives of BM 212: a new class of antimycobacterial agents. Design, synthesis, biological evaluation and study of their mode of action.
2010-01-01 Biava, M; Porretta, Gc; Poce, G; Alfonso, S; Battilocchio, C; DE LOGU, Alessandro; De Rossi, E; Manetti, F; Botta, M.
BM 579: a novel pyrrole derivative with improved antimycobacterial activity
2010-01-01 Biava, M; Porretta, Gc; Poce, G; Alfonso, S; Battilocchio, C; DE LOGU, Alessandro; Manetti, F; Botta, M.
Individuazione di nuovi target in MDR e XDR Mycobacterium tuberculosis mediante 1,5-difenil- e 1,5-diaril-2-etil-pirroli per lo sviluppo di nuovi agenti antitubercolari
2010-01-01 Agus, E; Biava, M; Porretta, Gc; Poce, G; De Rossi, E; Manetti, F; Botta, M; DE LOGU, Alessandro
Effetto di Inibitori delle COX-1 e COX-2 sullo sviluppo del biofilm di Candida albicans: studio della associazione di FANS e derivati azolici per la profilassi delle infezioni fungine contratte in ambiente ospedaliero
2010-01-01 Agus, E; Sanna, A; Piras, Cc; Serra, N; DE LOGU, Alessandro
dentification of a new Chemical Class of Potent Antimycobacterial Compounds
2010-01-01 Biava, M; Porretta, Gc; Poce, G; Alfonso, S; Battilocchio, C; DE LOGU, Alessandro; Manetti, F; Botta, M.
1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis and microbiological evaluation
2009-01-01 Biava, M; Porretta, Gc; Poce, G; DE LOGU, Alessandro; Meleddu, Rita; DE ROSSI, E; Manetti, F; Botta, M.
Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: part 2. Synthesis of rigid pyrazolones
2009-01-01 Castagnolo, D; Manetti, F; Radi, M; Bechi, B; Pagano, M; DE LOGU, Alessandro; Meleddu, Rita; Saddi, M; Botta, M.
Rifampicin-loaded liposomes for the passive targeting to alveolar macrophages: in vitro and in vivo evaluation
2009-01-01 Zaru, M; Sinico, Chiara; DE LOGU, Alessandro; Caddeo, Carla; Lai, Francesco; Manca, MARIA LETIZIA; Fadda, ANNA MARIA
Novel N-aryl- and N-heteryl phenazine-1-carboxamides as potential agents for the treatment of infections sustained by drug-resistant and multidrug-resistant Mycobacterium tuberculosis
2009-01-01 DE LOGU, Alessandro; LARISA H., Palchykovska; VALENTINA H., Kostina; Adriana, Sanna; Meleddu, Rita; Lorenza, Chisu; INNA V., Alexeeva; ANATOLY D., Shved
Novel N-aryl- and N-heteryl-phenazine-1-carboxamides as potential agents for the treatment of infections sustained by drug-resistant and MDR Mycobacterium tuberculosis
2009-01-01 DE LOGU, Alessandro; Palchykovska L., H; Kostina V., H; Sanna, A; Meleddu, Rita; Chisu, L; Alexeeva I., V; Shved, A. D.
ASPETTI MICROBIOLOGICI DELLA PRODUZIONE FARMACEUTICA
2009-01-01 DE LOGU, Alessandro
Effetto di FANS sulla formazione di biofilm di Candida albicans e potenziamento della attività di farmaci antifungini
2009-01-01 Agus, E; Piras, Cc; Casula, L; Serra, N; DE LOGU, Alessandro
Saggi e dosaggi microbiologici della Farmacopea
2009-01-01 DE LOGU, Alessandro
New pyrrole derivatives of BM 212: lead compound optimization strategy, Tuberculosis drug development. Targets, technologies and trials.
2009-01-01 Poce, G; Porretta, Gc; Borzi, F; DE LOGU, Alessandro; De Rossi, E; Manetti, F; Botta, M; Biava, M.
Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis
2009-01-01 Castagnolo, D; Radi, M; Dessì, F; Manetti, F; Saddi, M; Meleddu, Rita; DE LOGU, Alessandro; Botta, M.
Derivatives of BM 212: synthesis and biological evaluation of new derivatives with improved antimycobacterial activity.
2009-01-01 Biava, M; Porretta, Gc; Poce, G; Pompei, R; DE LOGU, Alessandro; Manetti, F; Botta, M.
BM212 and its derivatives: lead optimization of a new class of antimycobacterial agents.
2009-01-01 Poce, G; Porretta, Gc; DE LOGU, Alessandro; De Rossi, E; Manetti, F; Botta, M; Biava, M.
New pyrrole derivatives of BM 212: a new class of antimycobacterial agents.Design, synthesis, biological evaluation and study of their mode of action.
2009-01-01 Biava, M; Porretta, Gc; Poce, G; DE LOGU, Alessandro; Manetti, F; Botta, M.
| Titolo | Data di pubblicazione | Autore(i) | Rivista | Editore |
|---|---|---|---|---|
| Improving the physical chemical properties of a very promising class of pyrrole antimycobacterial agents | In corso di stampa | Poce, G; Alfonso, S; Cocozza, M; Porretta, Gc; Ballell, L; Bates, Rh; DE LOGU, Alessandro; Agus, E; De Rossi, E; Franzblau, Sg; Botta, M; Biava, M. | JOURNAL OF MEDICINAL CHEMISTRY | - |
| Synthesis, Biological Evaluation and Computational Studies of New Hydrazide Derivatives Containing 1,3,4-Oxadiazole as Antitubercular Agents | 1-gen-2022 | Zampieri, D.; Fortuna, S.; Romano, M.; De Logu, A.; Cabiddu, G.; Sanna, A.; Mamolo, M. G. | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
| Nano-Based Drug Delivery Systems of Potent MmpL3 Inhibitors for Tuberculosis Treatment | 1-gen-2022 | Hanieh, P. N.; Consalvi, S.; Forte, J.; Cabiddu, G.; De Logu, A.; Poce, G.; Rinaldi, F.; Biava, M.; Carafa, M.; Marianecci, C. | PHARMACEUTICS | - |
| Saggi e Dosaggi Microbiologici della Farmacopea. In Microbiologia Farmaceutica III Ed. Cap. 27 | 1-gen-2021 | De Logu, A. | - | EdiSES Università |
| Stafilococchi. In Microbiologia Farmaceutica. N. Carlone, R. Pompei, V. Tullio | 1-gen-2021 | De Logu, A | - | EdiSES Università |
| 6-Fluorophenylbenzohydrazides inhibit Mycobacterium tuberculosis growth through alteration of tryptophan biosynthesis | 1-gen-2021 | Consalvi, S.; Venditti, G.; Zhu, J.; Boshoff, H. I.; Arora, K.; De Logu, A.; Ioerger, T. R.; Rubin, E. J.; Biava, M.; Poce, G. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Aspetti Microbiologici della Produzione Farmaceutica | 1-gen-2021 | DE LOGU, Alessandro | - | EdiSES Università |
| Design, synthesis and antimycobacterial activity of benzoxazinone derivatives and open-ring analogues: Preliminary data and computational analysis | 1-gen-2019 | Zampieri, D.; Mamolo, M. G.; Filingeri, J.; Fortuna, S.; De Logu, A.; Sanna, A.; Zanon, D. | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| Imidazole and 1,2,4-triazole-based derivatives gifted with antitubercular activity: Cytotoxicity and computational assessment | 1-gen-2019 | Zampieri, Daniele; Cateni, Francesca; Moneghini, Mariarosa; Zacchigna, Marina; Laurini, Erik; Marson, Domenico; De Logu, Alessandro; Sanna, Adriana; Mamolo, Maria G | CURRENT TOPICS IN MEDICINAL CHEMISTRY | - |
| Novel Pyrazole-Containing Compounds Active against Mycobacterium tuberculosis | 1-gen-2019 | Poce, G.; Consalvi, S.; Venditti, G.; Alfonso, S.; Desideri, N.; Fernandez-Menendez, R.; Bates, R. H.; Ballell, L.; Barros Aguirre, D.; Rullas, J.; De Logu, A.; Gardner, M.; Ioerger, T. R.; Rubin, E. J.; Biava, M. | ACS MEDICINAL CHEMISTRY LETTERS | - |
| Naturally occurring Diels-Alder-type adducts from Morus nigra as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B | 1-gen-2018 | Mascarello, Alessandra; Orbem Menegatti, Angela Camila; Calcaterra, Andrea; Martins, Priscila Graziela Alves; Chiaradia-Delatorre, Louise Domeneghini; D'Acquarica, Ilaria; Ferrari, Franco; Pau, Valentina; Sanna, Adriana; De Logu, Alessandro; Botta, Maurizio; Botta, Bruno; Terenzi, Hernã¡n; Mori, Mattia | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Design, synthesis, SAR and biological investigation of 3-(carboxymethyl)rhodanine and aminothiazole inhibitors of Mycobacterium tuberculosis Zmp1 | 1-gen-2018 | Mori, Mattia; Deodato, Davide; Kasula, Mohan; Ferraris, Davide M; Sanna, Adriana; De Logu, Alessandro; Rizzi, Menico; Botta, Maurizio | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| In vivo potent BM635 analogue with improved drug-like properties | 1-gen-2018 | Poce, Giovanna; Cocozza, Martina; Alfonso, Salvatore; Consalvi, Sara; Venditti, Giulia; Fernandez-Menendez, Raquel; Bates, Robert H; Barros Aguirre, David; Ballell, Lluis; De Logu, Alessandro; Vistoli, Giulio; Biava, Mariangela | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Sherris. Microbiologia medica | 1-gen-2017 | DE LOGU, Alessandro; Batoni, Giovanna; Caputo, Antonella; Ceccherini Nelli, Luca; Cenci, Elio; Cocuzza, Clementina; Maria Cuffini, Anna; D'Agostini, Cartesio; Di Francesco, Paolo; Di Luca, Dario; Fadda, Daniela; Favalli, Cartesio; Galdiero, Marilena; Galdiero, Massimiliano; Gariglio, Marisa; Gaziano, Roberta; Giammanco, Anna; Grelli, Sandro; Landolfo, Santo; Massidda, Orietta; Mastromarino, Paola; Mattina, Roberto; Miragliotta, Giuseppe; Pagani, Laura; Palù, Giorgio; Perito, Stefano; Salvatore, Paola; Sanguinetti, Maurizio; Serra, Corrado; Sessa, Rosa; Sinibaldi Vallebona, Paola; Stefani, Stefania; Valenti, Piera | - | EMSI srl - Edizioni Mediche Scientifiche Internazionali |
| Antimycobacterial Activiy of New 1,4-Benzoxazine-2-one derivatives and its 2-(arylamino)-4-oxobut-2-enoate, ring-open analogues | 1-gen-2017 | Daniele, Zampieri; Marco, Bernecich; Maria Grazia, Mamolo; Sanna, Adriana; DE LOGU, Alessandro | PROCEEDINGS | - |
| Nuove strategie per lo sviluppo di farmaci antitubercolari: caratterizzazione di target alternativi e di fattori di virulenza in Mycobacterium tuberculosis | 1-gen-2016 | DE LOGU, Alessandro | - | - |
| Discovery of in vitro antitubercular agents through in silico ligand-based approaches | 1-gen-2016 | De Vita, D; Pandolfi, F; Cirilli, R; Scipione, L; Di Santo, R; Friggeri, L; Mori, M; Fiorucci, D; Maccari, G; Christopher, Rsa; Zamperini, C; Pau, V; DE LOGU, Alessandro; Tortorella, S; Botta, M. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Exploring the thiazole scaffold for the identification of new agents for the treatment of fluconazole resistant Candida | 1-gen-2016 | Meleddu, Rita; Distinto, Simona; Corona, Angela; Maccioni, Elias; Arridu, Antonella; Melis, Claudia; Bianco, Giulia; Matyus, Peter; Cottiglia, Filippo; Sanna, Adriana; DE LOGU, Alessandro | JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | - |
| Antimycobacterial activity of new N1-[1-[1-aryl-3-[4-(1H-imidazol-1-yl)phenyl]-3-oxo]propyl]-pyridine-2-carboxamidrazone derivatives | 1-gen-2016 | Zampieri, Daniele; Mamolo, Maria Grazia; Vio, Luciano; Romano, Maurizio; Skoko, Nataša; Baralle, Marco; Pau, Valentina; DE LOGU, Alessandro | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| Limonoids from Melia azedarach fruits as inhibitors of flaviviruses and mycobacterium tubercolosis | 1-gen-2015 | Sanna, Giuseppina; Madeddu, Silvia; Giliberti, Gabriele; Ntalli, Nikoletta G.; Cottiglia, Filippo; DE LOGU, Alessandro; Agus, Emanuela; Caboni, Pierluigi | PLOS ONE | - |
| HPLC-DAD-MS analysis and antiviral activity of different extracts and isolated costituents from Bituminaria bituminosa | 1-gen-2014 | Noccioli, C; Bertoli, A; Agus, E; DE LOGU, Alessandro; Pistelli, L. | CHEMISTRY OF NATURAL COMPOUNDS | - |
| Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection | 1-gen-2013 | Poce, G; Bates, Rh; Alfonso, S; Cocozza, M; Porretta, Gc; Ballell, L; Rullas, J; Ortega, F; DE LOGU, Alessandro; Agus, E; LA ROSA, Valentina; Pasca, Mr; De Rossi, E; Wae, B; Franzblau, Sg; Manetti, F; Botta, M; Biava, M. | PLOS ONE | - |
| 2-(2-cycloalkylidene hydrazin-1-yl)-4-aryl-1,3-thiazoles: a promising class of antifungal agents | 1-gen-2013 | Arridu, A.; Meleddu, R.; Bianco, Giulia; Distinto, Simona; DE LOGU, Alessandro; Matyus, P.; Maccioni, Elias | - | - |
| Stafilococchi | 1-gen-2012 | DE LOGU, Alessandro | - | Edises |
| Saggi e dosaggi microbiologici della Farmacopea | 1-gen-2012 | DE LOGU, Alessandro | - | Edises |
| Aspetti microbiologici della produzione farmaceutica | 1-gen-2012 | DE LOGU, Alessandro | - | Edises |
| MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212 | 1-gen-2012 | LA ROSA, Valentina; Poce, G; ORTIZ CANSECO, J; Buroni, S; Pasca, Mr; Biava, M; Raju, Rm; Poretta, Gc; Alfons, S; Battilocchio, C; Javid, B; Sorrentino, F; Ioerger, Tr; Sacchettini, Jc; Manetti, F; Botta, M.; DE LOGU, Alessandro; Rubin, Ej; DE ROSSI, E. | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | - |
| Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases | 1-gen-2011 | Casu, Laura; Cottiglia, Filippo; Leonti, Marco; DE LOGU, Alessandro; Agus, E; Tse Dinh, Yc; Lombardo, V; Sissi, C. | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| The MmpL3 protein is responsible for resistance to BM212, a lead antitubercular drug | 1-gen-2011 | Canseco, Jo; LA ROSA, Valentina; Luhaj, A; Battaglia, S; Buroni, S; Biava, M; DE LOGU, Alessandro; Manetti, F; Botta, M; De Rossi, E. | - | FEMS |
| Developing pyrrole-derived antimycobacterial agents: a rational lead optimization approach | 1-gen-2011 | Biava, M; Porretta, Gc; Poce, G; Battilocchio, C; Alfonso, S; DE LOGU, Alessandro; Manetti, F; Botta, M. | CHEMMEDCHEM | - |
| Identification of a novel pyrrole derivative endowed with antimycobacterial activity and protection index comparable to that of the current antitubercular drugs streptomycin and rifampin | 1-gen-2010 | Biava, M; Porretta, Gc; Poce, G; Battilocchio, C; Alfonso, S; DE LOGU, Alessandro; Serra, N; Manetti, F; Botta, M. | BIOORGANIC & MEDICINAL CHEMISTRY | - |
| Design, synthesis and microbiological characterization of 1,5-diphenyl and 1,5-diaryl-2-ethylpyrrole derivatives as new potential agents of infections sustained by MDR and XDR Mycobacterium tuberculosis. | 1-gen-2010 | Agus, E; Biava, M; Porretta, Gc; Poce, G; Serra, N; Sanna, A; De Rossi, E; Piras, Cc; Manetti, F; Botta, M; DE LOGU, Alessandro | - | - |
| New pyrrole derivatives of BM 212: a new class of antimycobacterial agents. Design, synthesis, biological evaluation and study of their mode of action. | 1-gen-2010 | Biava, M; Porretta, Gc; Poce, G; Alfonso, S; Battilocchio, C; DE LOGU, Alessandro; De Rossi, E; Manetti, F; Botta, M. | - | - |
| BM 579: a novel pyrrole derivative with improved antimycobacterial activity | 1-gen-2010 | Biava, M; Porretta, Gc; Poce, G; Alfonso, S; Battilocchio, C; DE LOGU, Alessandro; Manetti, F; Botta, M. | - | - |
| Individuazione di nuovi target in MDR e XDR Mycobacterium tuberculosis mediante 1,5-difenil- e 1,5-diaril-2-etil-pirroli per lo sviluppo di nuovi agenti antitubercolari | 1-gen-2010 | Agus, E; Biava, M; Porretta, Gc; Poce, G; De Rossi, E; Manetti, F; Botta, M; DE LOGU, Alessandro | - | - |
| Effetto di Inibitori delle COX-1 e COX-2 sullo sviluppo del biofilm di Candida albicans: studio della associazione di FANS e derivati azolici per la profilassi delle infezioni fungine contratte in ambiente ospedaliero | 1-gen-2010 | Agus, E; Sanna, A; Piras, Cc; Serra, N; DE LOGU, Alessandro | - | - |
| dentification of a new Chemical Class of Potent Antimycobacterial Compounds | 1-gen-2010 | Biava, M; Porretta, Gc; Poce, G; Alfonso, S; Battilocchio, C; DE LOGU, Alessandro; Manetti, F; Botta, M. | - | - |
| 1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: design, synthesis and microbiological evaluation | 1-gen-2009 | Biava, M; Porretta, Gc; Poce, G; DE LOGU, Alessandro; Meleddu, Rita; DE ROSSI, E; Manetti, F; Botta, M. | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - |
| Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: part 2. Synthesis of rigid pyrazolones | 1-gen-2009 | Castagnolo, D; Manetti, F; Radi, M; Bechi, B; Pagano, M; DE LOGU, Alessandro; Meleddu, Rita; Saddi, M; Botta, M. | BIOORGANIC & MEDICINAL CHEMISTRY | - |
| Rifampicin-loaded liposomes for the passive targeting to alveolar macrophages: in vitro and in vivo evaluation | 1-gen-2009 | Zaru, M; Sinico, Chiara; DE LOGU, Alessandro; Caddeo, Carla; Lai, Francesco; Manca, MARIA LETIZIA; Fadda, ANNA MARIA | JOURNAL OF LIPOSOME RESEARCH | - |
| Novel N-aryl- and N-heteryl phenazine-1-carboxamides as potential agents for the treatment of infections sustained by drug-resistant and multidrug-resistant Mycobacterium tuberculosis | 1-gen-2009 | DE LOGU, Alessandro; LARISA H., Palchykovska; VALENTINA H., Kostina; Adriana, Sanna; Meleddu, Rita; Lorenza, Chisu; INNA V., Alexeeva; ANATOLY D., Shved | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | - |
| Novel N-aryl- and N-heteryl-phenazine-1-carboxamides as potential agents for the treatment of infections sustained by drug-resistant and MDR Mycobacterium tuberculosis | 1-gen-2009 | DE LOGU, Alessandro; Palchykovska L., H; Kostina V., H; Sanna, A; Meleddu, Rita; Chisu, L; Alexeeva I., V; Shved, A. D. | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | - |
| ASPETTI MICROBIOLOGICI DELLA PRODUZIONE FARMACEUTICA | 1-gen-2009 | DE LOGU, Alessandro | - | Edises |
| Effetto di FANS sulla formazione di biofilm di Candida albicans e potenziamento della attività di farmaci antifungini | 1-gen-2009 | Agus, E; Piras, Cc; Casula, L; Serra, N; DE LOGU, Alessandro | - | - |
| Saggi e dosaggi microbiologici della Farmacopea | 1-gen-2009 | DE LOGU, Alessandro | - | - |
| New pyrrole derivatives of BM 212: lead compound optimization strategy, Tuberculosis drug development. Targets, technologies and trials. | 1-gen-2009 | Poce, G; Porretta, Gc; Borzi, F; DE LOGU, Alessandro; De Rossi, E; Manetti, F; Botta, M; Biava, M. | - | - |
| Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis | 1-gen-2009 | Castagnolo, D; Radi, M; Dessì, F; Manetti, F; Saddi, M; Meleddu, Rita; DE LOGU, Alessandro; Botta, M. | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| Derivatives of BM 212: synthesis and biological evaluation of new derivatives with improved antimycobacterial activity. | 1-gen-2009 | Biava, M; Porretta, Gc; Poce, G; Pompei, R; DE LOGU, Alessandro; Manetti, F; Botta, M. | - | - |
| BM212 and its derivatives: lead optimization of a new class of antimycobacterial agents. | 1-gen-2009 | Poce, G; Porretta, Gc; DE LOGU, Alessandro; De Rossi, E; Manetti, F; Botta, M; Biava, M. | - | - |
| New pyrrole derivatives of BM 212: a new class of antimycobacterial agents.Design, synthesis, biological evaluation and study of their mode of action. | 1-gen-2009 | Biava, M; Porretta, Gc; Poce, G; DE LOGU, Alessandro; Manetti, F; Botta, M. | - | - |
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