Università degli Studi di Cagliari
Inhibitory effect of positively charged triazine antagonists of prokinecitin receptors on the transient receptor vanilloid type-1 (TRPV1) channel
2015-01-01 Petrocellis, Luciano De; Moriello, Aniello Schiano; Byun, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol; Vázquez Romero, Ana; Garrido, Maria; Messeguer, Angel; Zhang, Fang Xiong; Zamponi, Gerald W; Deplano, Alessandro; Congiu, Cenzo; Onnis, Valentina; Balboni, Gianfranco; Marzo, Vincenzo Di
Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity
2015-01-01 Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Balboni, Gianfranco; Dedeoglu, Nurcan; Supuran, Claudiu T.
Design, Synthesis and Evaluation of new 2-(Arylidenehydrazino)pyrrole Derivatives as Potential Antitumor Agents
2014-01-01 Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Demurtas, M; Balboni, Gianfranco
Design, synthesis and pharmacological investigation on new FAAH inhibitors
2014-01-01 Onnis, Valentina; Congiu, Cenzo; Deplano, Alessandro; Demurtas, M; Cipriano, M; Fowler C., J; Morgillo C., M; Catalanotti, B.
An important role for prokineticin 2 in autoimmune CNS demyelination
2014-01-01 Abou hamdan, M.; Costanza, M.; Fontana, E.; Musio, S.; Di Dario, M.; Congiu, Cenzo; Onnis, Valentina; Lattanzi, R.; Negri, L.; Poliani, P. L.; Farina, C.; Balboni, Gianfranco; Steinman, L.; Pedotti, R.
Interaction and reactivity of synthetic aminoisoflavones with metal-free and metalassociated amyloid-beta
2014-01-01 Detoma, As; Krishnamoorthy, J; Nam, Y; Lee, Hj; Brender, Jr; Kochi, A; Lee, D; Onnis, Valentina; Congiu, Cenzo; Manfredini, S; Vertuani, S; Balboni, Gianfranco; Ramamoorthy, A; Lim, Mh
Halogenated triazinediones behave as antagonists of PKR1: in vitro and in vivo pharmacological characterization
2014-01-01 Lattanzi, R; Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Salvadori, S; Marconi, V; Maftei, D; Francioso, A; Ambrosio, C; Casella, I; Costa, T; Caltabiano, G; Matsoukas M., T; Balboni, Gianfranco; Negri, L.
A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists
2014-01-01 Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Salvadori, S; Marconi, V; Maftei, D; Negri, L; Lattanzi, R; Balboni, Gianfranco
Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties
2014-01-01 Congiu, Cenzo; Onnis, Valentina; Balboni, Gianfranco; Supuran, Ct
DESIGN, SYNTHESIS, AND EVALUATION OF (ISO)NIPECOTAMIDE AND PIPERAZINYLUREA DERIVATIVES AS TRPV1 MODULATORS
2013-01-01 Congiu, Cenzo; Onnis, Valentina; Schiano Moriello, A; Di Marzo, V.; De Petrocellis, L.
N-(2-HYDROXYARYL)AMIDES ENDOWED WITH ANTIPROLIFERATIVE ACTIVITY
2013-01-01 Onnis, Valentina; Congiu, Cenzo
Synthesis and biological evaluation of novel acylhydrazone derivatives as potential antitumor agents
2013-01-01 Congiu, Cenzo; Onnis, Valentina
Inhibition of fatty acid amide hydrolase and cyclooxygenase by the N-(3-methylpyridin-2-yl)amide derivatives of flurbiprofen and naproxen
2013-01-01 Cipriano, M.; Björklund, E.; Wilson, A. A.; Congiu, Cenzo; Onnis, Valentina; Fowler, C. J.
Inhibitory properties of ibuprofen and its amide analogues towards the hydrolysis and cyclooxygenation of the endocannabinoid anandamide
2013-01-01 Fowler, Cj; Björklund, E; Lichtman, Ah; Naidu, Ps; Congiu, Cenzo; Onnis, Valentina
Design, Synthesis, Biological Activity and SAR of New FAAH Inhibitors
2012-01-01 Onnis, Valentina; Congiu, Cenzo; Balboni, Gianfranco; Fowler, Cj
New antiproliferative diarylpyridines. design, synthesis, biological and photophysical characterization
2012-01-01 Congiu, Cenzo; Balboni, Gianfranco; Onnis, Valentina; Viola, G; Porcù, E; Vázquez, Me; Pazos, E.
Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context
2012-01-01 Wall, Rj; He, G; Denison, Ms; Congiu, Cenzo; Onnis, Valentina; Fernandes, A; Bell, Dr; Rose, M; Rowlands, Jc; Balboni, Gianfranco; Mellor, I. R.
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins
2012-01-01 Balboni, Gianfranco; Congiu, Cenzo; Onnis, Valentina; Maresca, A; Scozzafava, A; Winum, Jy; Maietti, A; Supuran, Ct
Prokineticin receptor 1 antagonist PC-10 as a biomarker for imaging inflammatory pain
2011-01-01 Jacobson, O; Weiss, Id; Niu, G; Balboni, Gianfranco; Congiu, Cenzo; Onnis, Valentina; Kiesewetter, Do; Lattanzi, R; Salvadori, S; Chen, X.
Dual action inhibitors of endocannabinoid metabolism and prostaglandin formation as novel analgesics
2010-01-01 Fowler, Cj; Onnis, Valentina
Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors
2010-01-01 Onnis, Valentina; Congiu, Cenzo; Björklund, E; Hempel, F; Söderström, E; Fowler, Cj
Synthesis and in vitro antitumor activity of new 4,5-dihydropyrazole derivatives
2010-01-01 Congiu, Cenzo; Onnis, Valentina; Vesci, L; Castorina, M; Pisano, C.
A novel inhibitor of fatty acid amide hydrolase, the enzyme responsible for the hydrolysis of the endocannabinoid anandamide
2009-01-01 Fowler, C; Bjorklund, E; Congiu, Cenzo; Onnis, Valentina
A novel inhibitor of fatty acid amide hydrolase, the enzyme responsible for the hydrolysis of the endocannabinoid anandamide
2009-01-01 Fowler, Cj; Björklund, E; Congiu, Cenzo; Onnis, Valentina
2-Acylhydrazino-5-arylpyrrole derivatives: Synthesis and antifungal activity evaluation
2009-01-01 Onnis, Valentina; DE LOGU, Alessandro; Cocco, Mt; Fadda, R; Meleddu, Rita; Congiu, Cenzo
The case for the development of novel analgesic agents targeting both fatty acid amide hydrolase and either cyclooxygenase or transient receptor potential vanilloid type 1
2009-01-01 FOWLER C., J; NAIDU P., S; Lichtman, A; Onnis, Valentina
Synthesis and evaluation of anticancer activity of 2-arylamino-6-trifluoromethyl-3-(hydrazonocarbonyl)pyridines
2009-01-01 Onnis, Valentina; Cocco, Mt; Fadda, R; Congiu, Cenzo
Synthesis and evaluation of antitumoral activity of ester and amide derivatives of 2-arylamino-6- trifluoromethyl-3-pyridinecarboxylic acids
2008-01-01 Onnis, Valentina; Cocco, Mt; Lilliu, V; Congiu, Cenzo
Design, synthesis, and in vitro antitumor activity of new 1,4-diarylimidazole-2-ones and their 2-thione analogues
2008-01-01 Congiu, Cenzo; Cocco, Mt; Onnis, Valentina
Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin
2007-01-01 Holt, S; Paylor, B; Boldrup, L; Alajakku, K; Vandevoorde, S; Sundstrom, A; Cocco, Mt; Onnis, Valentina; Fowler, Cj
Synthesis and in vitro antitumoral activity of new 3,5-dicyanopyridine derivatives
2007-01-01 Cocco, Mt; Congiu, Cenzo; Lilliu, V; Onnis, Valentina
Further studies on the effect of lysine at the C-terminus of the Dmt-Tic opioid pharmacophore
2007-01-01 Balboni, Gianfranco; Onnis, Valentina; Congiu, Cenzo; Zotti, M; Sasaki, Y; Ambo, A; BRYANT S., D; Jinsmaa, Y; LAZARUS L., H; Lazzari, I; Trapella, C; Salvadori, S.
Synthesis, characterisation and insulin-mimetic activity of oxovanadium(IV) complexes with amidrazone derivatives
2007-01-01 COCCO M., T; Onnis, Valentina; Ponticelli, G; Meier, B; Rehder, D; Garribba, E; Micera, G.
Amidrazones as Precursor of Biologically Active Compounds. Synthesis of Diaminopyrazoles for Evaluation of Anticancer Activity
2006-01-01 Cocco, Mt; Congiu, Cenzo; Lilliu, V; Onnis, Valentina
Effect of lysine at C-terminus of the Dmt-Tic opioid pharmacophore
2006-01-01 Balboni, Gianfranco; Onnis, Valentina; Congiu, Cenzo; Zotti, M; Sasaki, Y; Ambo, A; Bryant, Sd; Jinsmaa, Y; Lazarus, Lh; Trapella, C; Salvadori, S.
Synthesis and in vitro antitumoral activity of new hydrazinopyrimidine-5-carbonitrile derivatives
2006-01-01 Cocco, Mt; Congiu, Cenzo; Lilliu, V; Onnis, Valentina
Synthesis and antiproliferative activity of 2,6-Dibenzylamino-3,5-dicyanopyridines on human cancer cell lines
2005-01-01 Cocco, Mt; Congiu, Cenzo; Lilliu, V; Onnis, Valentina
New potential anticancer agents based on the anthranilic acid scaffold: synthesis and evaluation of biological activity
2005-01-01 Congiu, Cenzo; Cocco, Mt; Lilliu, V; Onnis, Valentina
In vitro antimycobacterial activity of newly synthesised S-alkylisothiosemicarbazone derivatives and synergistic interactions in combination with rifamycins against Mycobacterium avium
2005-01-01 DE LOGU, Alessandro; Onnis, Valentina; Saddi, M; Sanna, C; Congiu, Cenzo; Borgna, R; Cocco, M. T.
Synthesis and structural studies of 3-acylamino-4-amino-2,3-dihydro-2-iminothiazole-5-carboxylates and 4-acylhydrazino-2-aminothiazole-5-carboxylates
2004-01-01 Cocco, Mt; Congiu, Cenzo; Onnis, Valentina
Synthesis of new N-(2-(trifluoromethyl)pyridin-4-yl)anthranilic acid derivatives and their evaluation as anticancer agents
2004-01-01 Cocco, Mt; Congiu, Cenzo; Lilliu, V; Onnis, Valentina
Synthesis of new 2-arylamino-6-trifluoromethylpyridine-3-carboxylic acid derivatives and investigation of their analgesic activity
2004-01-01 Cocco, Mt; Congiu, Cenzo; Onnis, Valentina; Morelli, Micaela; Felipo, V; Cauli, O.
New bis(pyridyl)methane derivatives from 4-hydroxy-2-pyridones: synthesis and antitumoral activity
2003-01-01 Cocco, Mt; Congiu, Cenzo; Onnis, Valentina
Synthesis and in vitro antitumoral activity of new N-phenyl-3-pyrrolecarbothioamides
2003-01-01 Cocco, Mt; Congiu, Cenzo; Onnis, Valentina
Synthesis of ibuprofen heterocyclic amides and investigation of their analgesic and toxicological properties
2003-01-01 Cocco, Mt; Congiu, Cenzo; Onnis, Valentina; Morelli, Micaela; Cauli, O.
Attività antimicobatterica di nuovi S-alchilisotiosemicarbazoni e potenziamento dell'attività di rifabutina, rifampicina e amikacina nei confronti di Mycobacterium avium
2002-01-01 DE LOGU, Alessandro; Onnis, Valentina; Pellerano, Ml; Pusceddu, Mc; Saddi, B; Congiu, Cenzo; Marcialis, Ma; Cocco, Mt
Synthesis and antimycobacterial activity of new S-alkylisotiosemicarbazone derivatives
2002-01-01 Cocco, M. T.; Congiu, Cenzo; Onnis, Valentina; Pellerano, M. L.; DE LOGU, Alessandro
Activity of a new class of isonicotinoylhydrazones used alone and in combination with isoniazid, rifampicin, ethambutol, para-aminosalicylic acid and clofazimine against Mycobacterium tuberculosis
2002-01-01 DE LOGU, Alessandro; Onnis, Valentina; Saddi, B; Congiu, Cenzo; Schivo, Ml; Cocco, Mt
Crystal and molecular structure of acetamidrazone derivatives
2002-01-01 Ianelli, S.; Pelosi, G.; Ponticelli, G.; Cocco, M. T.; Onnis, Valentina
Synthesis and antitumor evaluation of 6-thioxo-, 6-oxo- and 2,4-dioxopyrimidine derivatives
2001-01-01 Cocco, Mt; Congiu, Cenzo; Onnis, Valentina; Piras, R.
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