University of Cagliari
BASIC PRINCIPLES OF DRUG DISCOVERY AND DEVELOPMENT
Students will gain a comprehensive overview of the key aspects of drug discovery and development, focusing on medicinal chemistry, pharmaceutical technology, and pharmacology.
Supporting materials to help students approach the medicinal chemistry section of the course will be provided here.
02 October 2025
- BASIC PRINCIPLES-0-INTRO
- BASIC PRINCIPLES-1-DrugDiscoveryProcess
- BASIC PRINCIPLES-2- New trends in DD
- BASIC PRINCIPLES-3-Basic-conceptsMC
- BASIC PRINCIPLES-3-Basic-conceptsMC
- BASIC PRINCIPLES-4-Optimization-SAR-Pharmacophore
- BASIC PRINCIPLES-5-Pharmacokinetics-I
- BASIC PRINCIPLES-5-Pharmacokinetics-II-and ex
- BASIC PRINCIPLES-5-Pharmacokinetics-III
- BASIC PRINCIPLES-6-PD and Structural Analysis
- BASIC PRINCIPLES-6-Pharmacodynamics-Protein and NA Targets
- BASIC PRINCIPLES-7-Peptides and Protein Therapeutics
- BASIC PRINCIPLES-7-Small Nucleic Acid Drugs
- BASIC PRINCIPLES-summary-DD-Design-SAR-PK-PD
- BASIC PRINCIPLES-Exam and Seminars info
Student office hours: preferably Monday to Friday, from 12:00 PM to 1:00 PM, anyway always by appointment contacting me via email at s.distinto@unica.it or by phone at 0706758550 or in Teams.
Books
B.E. Blass. Basic principles of drug discovery and development. 2nd edition. Academic Press, Elsevier, 2021.
D.J.A. Crommelin, R.D. Sindelar, B. Meibohm. Pharmaceutical Biotechnology, Fundamentals and Applications Springer
A.R. Leach. Molecular Modelling, Principles and Applications - Pearson College Div.
Mailing list AA 2025-2026:
Fill the form https://forms.office.com/e/3bwTSzTYCM
(link open from 03/10 to 15/10)