Metabolomic Characteristics in Endometriosis Patients

Angioni, Stefano

First

;Saponara, Stefania;Succu, Antonio G.;Sigilli, Marco;Scicchitano, Francesco;D’Alterio, Maurizio Nicola

Last

2020-01-01

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Abstract

Endometriosis is a benign gynaecological disease that may cause infertility. Its diagnosis is often delayed due to the similarity of its symptoms with other diseases. Chronic diseases like endometriosis may impair the metabolism of different compounds like sugars, amino acids, simple and complex lipids and may alter their levels in many biological samples. Many studies have investigated the role of different biomarkers that could be useful for non-invasive diagnosis of early-stage endometriosis. These biomarkers were evaluated in various biological samples (follicular fluids, blood, urines) using different techniques, such as magnetic resonance imaging and mass spectrometry. In this chapter, we analyse the recent scientific evidence about using a metabolomic approach for the early diagnosis of endometriosis, as well as for its recurrence and treatment.