Metabolomic Investigation of β-Thalassemia in Chorionic Villi Samples

Murgia, Federica;Peddes, Cristina;Tronci, Laura;Atzori, Luigi
Last
Supervision
2019-01-01

Abstract

Beta-thalassemias are blood disorders characterized by poorly understood clinical phenotypes ranging from asymptomatic to severe anemia. Metabolic composition of the human placenta could be affected by the presence of pathological states such as β-thalassemia. The aim of our study was to describe metabolic changes in chorionic villi samples of fetuses affected by β-thalassemia compared to a control group by applying a metabolomics approach.
2019
2019
Inglese
JOURNAL OF CLINICAL MEDICINE
8
6
9
WOS:000475349300042
2-s2.0-85079596162
31195667
https://www.mdpi.com/2077-0383/8/6/798
Esperti anonimi
internazionale
scientifica
arachidonic acid metabolism; chorionic villi samples; gas chromatography–mass spectrometry; metabolomics; pentose phosphate pathway; β-thalassemia
no
Monni, Giovanni; Murgia, Federica; Corda, Valentina; Peddes, Cristina; Iuculano, Ambra; Tronci, Laura; Balsamo, Antonella; Atzori, Luigi
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
8
open
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