Reaction of enaminonitriles with isocyanates. Synthesis of new 2-oxo- and 6-oxopyrimidines
CONGIU, CENZO;ONNIS, VALENTINA
1994-01-01
Abstract
The reaction of enaminonitriles 1 with aryl or benzyl isocyanates afforded C-3-5 or N-adducts 6-8 or a mixture of both depending on the substitution pattern of the considered enaminonitrile. The one-step synthesis of 6-oxopyrimidines 9-11 and 2-oxopyrimidines 12-14 by cyclization of compounds 3-5 and 6-8 respectively is also described.File | Size | Format | |
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