A new and efficient synthesis of phthalazin-1(2H)-ones

Bernard AM;Cocco MT;CONGIU, CENZO;ONNIS, VALENTINA;Piras PP

1998-01-01

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Abstract

2-Amino-2-(aroylhydrazono)ethyl aryl ethers, readily obtained from a wide range of aryloxyacetonitriles, are converted to phthalazin-1(2H)-ones derivatives in high yields by heating in PrOH in the presence of p-TsOH.