PROTEIN MODELING ACS 2024-2025
The teacher will directly provide the support material to the students, considering the guidelines that the teacher gave in the first lesson.
Module of protein modeling (CFU 2+1)
• Introduction to protein structure and the folding mechanism
• Uniprot and other useful biological DBs
• Protein Data Bank and overview of experimental methods to obtain the 3D structure model of a macromolecule
• File formats for small- and macro-molecules
• PDB models analysis
• 3D visualization tools
• Sequence alignments
• 3D alignments
• Methods for secondary structure prediction
• Methods for 3D structure prediction
• Validation and analysis of models
• Overview of structure-based computational methods
• Introduction to System Biology
13 October 2024