University of Cagliari
One-step synthesis of thieno[3,2-b]thiophene 1,1-dioxide derivatives
FATTUONI, CLAUDIA;CABIDDU, MARIA GRAZIA;CADONI, ENZO;
2007-01-01
Abstract
A rapid.. one-step synthesis of thieno[3,2-b]thiophene 11-dioxide derivatives using direct bimetalation of 3-(methylsulfoilyl)thiophene and ring Closure with esters is described. Two iterative, one-pot monometalations of the same substrate allowed bifunctionalization with either equal or different groups, after electrophilic quenching.
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