Failure of ketamine to interact with opiate receptors

FRATTA, WALTER;CASU, MARIANO;LOVISELLI, ANDREA;
1980-01-01

Abstract

Ketamine, an anesthetic agent endowed with several morphine-like effects, failed to displace 3H-dihydromorphine or 3H-methionine-enkephalin from opiate receptors in the rat brain synaptosomal-mitochondrial membrane preparations. Furthermore, ketamine-induced analgesia in rats was not antagonized by naloxone, suggesting that this effect is not mediated by opiate receptors.
1980
Inglese
EUROPEAN JOURNAL OF PHARMACOLOGY
61
4
389
391
3
2-s2.0-0018844949
6245894
Esperti anonimi
scientifica
no
Fratta, Walter; Casu, Mariano; Balestrieri, A; Loviselli, Andrea; Biggio, G; Gessa, Gl
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
6
none
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