Flash photolysis of caged compounds in the cilia of olfactory sensory neurons

Boccaccio A;SAGHEDDU, CLAUDIA;Menini A.

2011-01-01

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Abstract

Photolysis of caged compounds allows the production of rapid and localized increases in the concentration of various physiologically active compounds(1). Caged compounds are molecules made physiologically inactive by a chemical cage that can be broken by a flash of ultraviolet light. Here, we show how to obtain patch-clamp recordings combined with photolysis of caged compounds for the study of olfactory transduction in dissociated mouse olfactory sensory neurons.