Alberto Cauli
Nutrient availability links mitochondria, apoptosis, and obesity
PINTUS, FRANCESCA;
2012-01-01
Abstract
Mitochondria are the dominant source of the cellular energy requirements through oxidative phosphorylation, but they are also central players in apoptosis. Nutrient availability may have been the main evolutionary driving force behind these opposite mitochondrial functions: production of energy to sustain life and release of apoptotic proteins to trigger cell death. Here, we explore the link between nutrients, mitochondria and apoptosis with known and potential implications for age‐related decline and metabolic syndromes.File | Size | Format | |
---|---|---|---|
22_Pintus et al_Aging_2012.pdf open access
Type: versione editoriale
Size 1.07 MB
Format Adobe PDF
|
1.07 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.