Opioid peptides. Partially modified retro-inverso dermorphin analogues. XIII

BALBONI, GIANFRANCO;
1989-01-01

Abstract

We studied the effect of partial retro-inverso modification of a selected peptide bond of dermorphin (H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2) related peptides. The drastic loss of mu-receptor affinity following introduction of retro-inverso peptide bond between Phe1-D-Ala2 in the new peptide analogues, emphasized the importance of this backbone in the dermorphin peptides.
1989
Inglese
IL FARMACO
44
1083
1093
11
A1989CP30300008
2-s2.0-0024849047
Esperti anonimi
I synthesized some of the peptides.
Marastoni, M; Balboni, Gianfranco; Tomatis, R; Salvadori, S; Borea, Pa; Uccelli, L.
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
6
none
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