ZnO-mediated regioselective C-arylsulfonylation of indoles: A facile solvent-free synthesis of 2- and 3-sulfonylindoles and preliminary evaluation of their activity against drug-resistant mutant HIV-1 reverse transcriptases (RTs)

TOCCO, GRAZIELLA;BEGALA, MICHELA;ESPOSITO, FRANCESCA;CABONI, PIERLUIGI;CANNAS, VALERIA;TRAMONTANO, ENZO
2013-01-01

Abstract

A ZnO-mediated one-pot solvent-free protocol for the regioselective C-arylsulfonylation of indoles is described and some novel derivatives were tested on wild type and non-nucleoside inhibitor resistant K103N and Y181C HIV-1 reverse transcriptases (RTs).
2013
Inglese
TETRAHEDRON LETTERS
54
46
6237
6241
5
WOS:000326009300022
2-s2.0-84885482045
Esperti anonimi
internazionale
scientifica
Regioselectivity, C-Arylfonylation, Indoles, Non-nucleoside inhibitor, HIV-1 RT
no
Tocco, Graziella; Begala, Michela; Esposito, Francesca; Caboni, Pierluigi; Cannas, Valeria; Tramontano, Enzo
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
6
reserved
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