Tandem Baeyer–Villiger/Wittig/oxa-Michael addition: One-step to 5-substituted γ-lactones

Barranco S.;Caboni P.;Frongia A.
2023-01-01

Abstract

The results reported in this study provide a practical protocol for the construction, in one single step of synthetically important γ-lactones in good yields starting from α-hydroxy cyclobutanone, H2O2 and several stabilized phosphonium ylides. Our synthetic strategy relies on a tandem Baeyer–Villiger oxidation/Wittig reaction/oxa-Michael addition.
2023
Inglese
TETRAHEDRON LETTERS
123
154545
4
WOS:001015178500001
2-s2.0-85159721931
Esperti anonimi
internazionale
scientifica
Baeyer–Villiger; Strained rings; Tandem reactions; γ-Lactones
no
Barranco, S.; Cuccu, F.; Caboni, P.; Frongia, A.
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
4
partially_open
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