Next-generation sequencing analysis of cholangiocarcinoma identifies distinct IDH1-mutated clusters

Loi, Eleonora
Co-prime
;Scartozzi, Mario;Lai, Eleonora;Pretta, Andrea;Cascinu, Stefano;Patrizia, Zavattari
Penultimate
;Casadei-Gardini, Andrea
2022-01-01

Abstract

IDH1-mutated intrahepatic cholangiocarcinomas (IDH1m iCCAs) could be treated with anti-IDH1 drugs, although the high heterogeneity in this class of tumours could limit treatment efficacy.
2022
Cholangiocarcinoma
Clustering analysis
Genomic profiling
IDH1 mutation
Next-generation sequencing
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