Next-generation sequencing analysis of cholangiocarcinoma identifies distinct IDH1-mutated clusters

Loi, Eleonora
Co-prime
;Scartozzi, Mario;Lai, Eleonora;Pretta, Andrea;Cascinu, Stefano;Patrizia, Zavattari
Penultimate
;Casadei-Gardini, Andrea
2022-01-01

Abstract

IDH1-mutated intrahepatic cholangiocarcinomas (IDH1m iCCAs) could be treated with anti-IDH1 drugs, although the high heterogeneity in this class of tumours could limit treatment efficacy.
2022
2022
Inglese
EUROPEAN JOURNAL OF CANCER
175
299
310
12
WOS:000898739000001
2-s2.0-85138765321
36182816
https://www.ejcancer.com/article/S0959-8049(22)00519-6/fulltext
Esperti anonimi
internazionale
scientifica
Cholangiocarcinoma
Clustering analysis
Genomic profiling
IDH1 mutation
Next-generation sequencing
sì
Rimini, Margherita; Loi, Eleonora; Fabregat-Franco, Carles; Burgio, Valentina; Lonardi, Sara; Niger, Monica; Scartozzi, Mario; Raposelli, Ilario G; Aprile, Giuseppe; Ratti, Francesca; Pedica, Federica; Verdaguer, Helena; Rizzato, Mario; Nichetti, Federico; Lai, Eleonora; Cappetta, Alessandro; Macarulla, Teresa; Fassan, Matteo; De Braud, Filippo; Pretta, Andrea; Simionato, Francesca; De Cobelli, Francesco; Aldrighetti, Luca; Fornaro, Lorenzo; Cascinu, Stefano; Zavattari, Patrizia; Casadei-Gardini, Andrea
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
27
reserved
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