Marco Giovanni Nieddu
A trustworthy mechanochemical route to isocyanides
Basoccu, FrancescoFirst
;Cuccu, Federico;Casti, Federico;Mocci, Rita;Fattuoni, Claudia;Porcheddu, Andrea
Last
2022-01-01
Abstract
Isocyanides are hardly produced, dramatically sensitive to purification processes, and complex to handle as synthetic tools. Notwithstanding, they represent one of the most refined and valuable compounds for accessing sophisticated and elegant synthetic routes. A unique interest has always been addressed to their production, though their synthetic pathways usually involve employing strong conditions and toxic reagents. The current paper intends to provide a conceptually innovative synthetic protocol for mechanochemical isocyanide preparation, simultaneously lowering the related reagents' toxicity and improving their purification in a straightforward procedure.File | Size | Format | |
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Beilstein 2022.pdf open access
Type: versione editoriale
Size 4.18 MB
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4.18 MB | Adobe PDF | View/Open |
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