University of Cagliari
A Catalytic One-Pot Synthesis of Indolyl Cyclobutanones
Porcu S.First
;Frongia A.;Secci F.
Last
2021-01-01
Abstract
A general strategy for the synthesis of indolyl cyclobutanones via a tandem Bronsted acid catalyzed 2-hydroxycyclobutanone activation-indole nucleophilic addition has been exploited. The procedure leads to a wide range of 2- and 3-functionalized indole derivatives in good to high yields with broad substrate scope.
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