A Catalytic One-Pot Synthesis of Indolyl Cyclobutanones

Porcu S.
First
;
Frongia A.;Secci F.
Last
2021-01-01

Abstract

A general strategy for the synthesis of indolyl cyclobutanones via a tandem Bronsted acid catalyzed 2-hydroxycyclobutanone activation-indole nucleophilic addition has been exploited. The procedure leads to a wide range of 2- and 3-functionalized indole derivatives in good to high yields with broad substrate scope.
2021
2020
Inglese
53
5
925
932
8
Esperti anonimi
internazionale
scientifica
Bronsted acids; Catalysis; Cyclobutanones; Indoles; Tandem reactions
no
Porcu, S.; Rodriguez, C. A.; Frongia, A.; Secci, F.
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
4
reserved
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