Glomeruloid reactive angioendotheliomatosis in a woman with systemic lupus erythematosus and antiphospholipid syndrome mimicking reticular erythematous mucinosis

Ferreli, Caterina

First

Data Curation

;Atzori, Laura

Second

Writing - Original Draft Preparation

;Rongioletti, Franco

Last

Supervision

2021-01-01

---

Abstract

The umbrella term ‘‘cutaneous reactive angioma- toses’’ was introduced in 2003 to include uncommon angioproliferative (capillary) cutaneous conditions, which present with variable clinical features and involve patients with a variety of underlying systemic conditions.1 Histologically, these disorders are char- acterized by different patterns of intravascular or extravascular lobular or diffuse hyperplasia of endo- thelial cells, pericytes, and, sometimes, histiocytes, mostly throughout the dermis.1 The first condition to be described was reactive angioendotheliomatosis (RAE), which is usually associated with prothrom- botic conditions.1 We report a case of RAE in its rare glomeruloid variant, occurring in a woman with systemic lupus erythematosus (SLE) and antiphos- pholipid syndrome (APS), which is notable because it mimics reticular erythematous mucinosis (REM).