Pseudoepitheliomatous keratotic and micaceous balanitis: low-risk human papilloma virus detection in two further cases

Corbeddu, Marialuisa;Pilloni, Luca

Co-prime

Writing - Original Draft Preparation

;Satta, Roberta;Atzori, Laura

Co-prime

Writing - Review & Editing

;Rongioletti, Franco

Last

Supervision

2021-01-01

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Abstract

We report two cases of histologically documented pseudoepitheliomatous keratotic and micaceous balanitis in middle-aged male patients, which showed positivity for low-risk serotype human papillomavirus DNA. To our knowledge, only one other case has been documented. Further immunohistochemical proliferative markers were performed and compared to literature findings in penile epithelial proliferations. Evolution to invasive verrucous carcinoma has been associated with absence of HPV DNA. Thus, if confirmed by further studies, HPV testing should be included in pseudoepitheliomatous keratotic and micaceous balanitis assessment to address prognosis, and management.