Visible-Light Photoredox-Catalyzed Amidation of Benzylic Alcohols

Gaspa S.;Tilocca M.;Porcheddu A.;Azzena U.;
2020-01-01

Abstract

A new photocatalyzed route to amides from alcohols and amines mediated by visible light is presented. The reaction is carried out in ethyl acetate as a solvent. Ethyl acetate can be defined a green and bio-based solvent. The starting materials such as the energy source are easily available, stable, and inexpensive. The reaction has shown to be general and high yielding.
2020
oxidative amidation; carboxylic-acids; transition-metal; amide synthesis; amines; aldehydes; alpha; hydrocarbons; chloride; cleavage
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