The Treatment of Acute Diaphyseal Long-bones Fractures with Orthobiologics and Pharmacological Interventions for Bone Healing Enhancement: A Systematic Review of Clinical Evidence

Marongiu, Giuseppe;Contini, Andrea;Capone, Antonio
2020-01-01

Abstract

The healing of long bones diaphyseal fractures can be often impaired and eventually end into delayed union and non-union. A number of therapeutic strategies have been proposed in combination with surgical treatment in order to enhance the healing process, such as scaffolds, growth factors, cell therapies and systemic pharmacological treatments. Our aim was to investigate the current evidence of bone healing enhancement of acute long bone diaphyseal fractures.
2020
2020
Inglese
BIOENGINEERING
7
1
17
WOS:000523493300018
2-s2.0-85083737763
32102398
https://www.mdpi.com/2306-5354/7/1/22
Esperti anonimi
internazionale
scientifica
bone healing; cell therapies; diamond concept; growth factors; long-bones; scaffolds; shaft fractures; teriparatide
no
Marongiu, Giuseppe; Contini, Andrea; Cozzi Lepri, Andrea; Donadu, Matthew; Verona, Marco; Capone, Antonio
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
6
open
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