Antibacterial activity of two products containing hydrogen peroxide and silver salts

DEL NERO S;MARCHESE G;MANDAS D;LICIARDI M;DENOTTI G;ORRU, GERMANO

2012-01-01

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Abstract

Abstract Objectives The purpose of this study was to examine the antibiofilm and the antibacterial activity efficacy of H2O2 alone and combined with silver salts. Materials and methods We used standard and innovative methods to assess the antibacterial effects of (i) H2O2 at 300 e 600ppm (parts per million), and at 3%; (ii) the same H2O2 concentrations with the addition of Ag+ salts at 5 and 10ppm, against a large number of microorganisms, in planctonic and sessile (biofilm) forms. Results All of the microorganisms tested (including some nosocomial pathogens, such as Legionella pneumophila, Staphylococcus aureus, Pseudomonas aeruginosa) were inhibited at concentrations lower than those commonly used in dental unit waterlines (MIC < 600ppm) Conclusions H2O2 with silver salts displayed greater antibiofilm efficacy than the negative control (H2O2 without silver ions).