Tandem Wittig Reaction-Ring Contraction of Cyclobutanes: a Route to Functionalized Cyclopropanecarbaldehydes

L. Serusi
Second
;A. Luridiana;F. Secci;P. Caboni;A. Frongia
Last
2019-01-01

Abstract

An original tandem reaction consisting of a Wittig reaction–ring contraction process between α‐hydroxycyclobutanone and phosphonium ylides has been developed. Highly functionalised cyclopropanecarbaldehydes are obtained in good to high yields.
2019
STEREOCONTROLLED SYNTHESIS; CYCLOPROPYL KETONES; SECONDARY ALCOHOLS; DERIVATIVES; REARRANGEMENT
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