New Variations on the Theme of Gold(III) C^N^N Cyclometalated Complexes as Anticancer Agents: Synthesis and Biological Characterization

Laura Maiore;Massimiliano Arca;
2018-01-01

Abstract

A new series of novel (C∧N∧N) cyclometalated gold(III) complexes have been characterized for their structural and spectroscopic properties. The anticancer activities of the compounds have been studied in vitro, and their reactivity with model biomolecules has been elucidated by mass spectrometry techniques, evidencing an unexpected preference for binding to nucleic acids with respect to proteins and amino acids.
2018
2018
Inglese
INORGANIC CHEMISTRY
57
23
14852
14865
14
WOS:000452344400045
2-s2.0-85057595642
30457328
Esperti anonimi
internazionale
scientifica
sì
Carboni, Silvia; Zucca, Antonio; Stoccoro, Sergio; Maiore, Laura; Arca, Massimiliano; Ortu, Fabrizio; Artner, Christian; Keppler, Bernhard K.; Meier-Menches, Samuel M.; Casini, Angela; Agostina Cinellu, Maria
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
11
reserved
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