Patti Alessandra
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Alessandra Patti

Brønsted Acid Mediated Cascade Reaction to Access 3-(2-Bromoethyl)benzofurans

Porcu, Stefania
First
;DEMURO, STEFANIA;Luridiana, Alberto;Frongia, Angelo;Sarais, Giorgia;Secci, Francesco
Last
2018-01-01

Abstract

A unified protocol for the construction of 3-(2-bromoethyl)benzofurans and 2-(benzofuran-3-yl)ethylamines from bis[(trimethylsilyl)oxy]cyclobutene has been developed. This mild and facile strategy was applied for the synthesis of a series of 5-HT serotonin receptor agonists, underlining its potential for the syntheses of bioactive compounds and natural products.
2018
Biochemistry; Physical and Theoretical Chemistry; Organic Chemistry
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