Brønsted Acid Mediated Cascade Reaction to Access 3-(2-Bromoethyl)benzofurans

Porcu, Stefania
First
;DEMURO, STEFANIA;Luridiana, Alberto;Frongia, Angelo;Sarais, Giorgia;Secci, Francesco
Last
2018-01-01

Abstract

A unified protocol for the construction of 3-(2-bromoethyl)benzofurans and 2-(benzofuran-3-yl)ethylamines from bis[(trimethylsilyl)oxy]cyclobutene has been developed. This mild and facile strategy was applied for the synthesis of a series of 5-HT serotonin receptor agonists, underlining its potential for the syntheses of bioactive compounds and natural products.
2018
2018
Inglese
ORGANIC LETTERS
20
23
7699
7702
4
WOS:000452930100077
2-s2.0-85056853341
30422665
http://pubs.acs.org/journal/orlef7
https://pubs.acs.org/doi/10.1021/acs.orglett.8b03429
Esperti anonimi
internazionale
scientifica
Biochemistry; Physical and Theoretical Chemistry; Organic Chemistry
sì
Porcu, Stefania; Demuro, Stefania; Luridiana, Alberto; Cocco, Andrea; Frongia, Angelo; Aitken, David J.; Charnay-Pouget, Florence; Guillot, Regis; Sar ...espandi
1.1 Articolo in rivista
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
10
reserved
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