University of Cagliari
Italian guidelines in pemphigus - adapted from the European Dermatology Forum (EDF) and European Academy of Dermatology and Venerology (EADV)
Atzori LMember of the Collaboration Group
;COSTANZO, GIULIA ANNA MARIA LUIGIA;Papini M;
2018-01-01
Abstract
Pemphigus is a life threatening autoimmune epidermal blistering disease involving skin and mucous membranes. Pemphigus usually affects middle age men and women involving oral mucosa first and then spreading on the skin. It is caused by the presence of autoantibodies (IgG and less frequently by IgA) directed against desmogleins, and/or other glycoproteins that plays a critical role in cell-cell attachment. Upon a predisposing genetic background, different agents have been shown to act as triggers for the pathogenesis of pemphigus. This guideline for the diagnosis and treatment of pemphigus has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum in collaboration with the European Academy of Dermatology and Venereology. It summarizes evidence-based and expert-based recommendations (S2 level).
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| File | Size | Format | |
|---|---|---|---|
| pemfigo guidelines.pdf Solo gestori archivio
Type: versione post-print
Size 320.95 kB
Format Adobe PDF
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320.95 kB | Adobe PDF | & nbsp; View / Open Request a copy |
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