USE OF GAS CHROMATOGRAPHY ORAL CHROMA™ IN THE ASSESSMENT OF VOLATILE SULFUR COMPOUNDS FOR BREATH’S ANALYSIS IN ORAL AND GASTRIC AFFECTION

F. Coghe;M. P. Contu;P. Ferraguti;N. Arena;G. Bogo;R. Faa;M. Pautasso;G. Serreli

Conceptualization

;B. De Magistri4;A. Piras;V. Piras

Penultimate

Project Administration

;G. Orrù

Last

Methodology

2015-01-01

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Abstract

Introduction: Breathomics (Breath-based metabolomics) is a new biotechnology approach that allow us to diagnose some human diseases by the oral breath analysis.The method is based on the identi#cation and quanti#cation of volatile organic compound (VOC) in breath, by a new portable gas chromatography’s tools such as Oral Chroma®. This instrument is able to detect and quantify three different volatile sulfur compounds, VSC ( H2S, CH3S ,(CH3)2S) in 5 ml of oral breath, in fast time and with good analytical accuracy. In addition, different authors recently have been described as a comparative analysis of VSC could be useful in the diagnosis of different oral or systemic diseases such as: (i) oral tongue halitosis or/and gastric affection such as Helicobacter pylori infection