An Environmentally Sustainable Mechanochemical Route to Hydroxamic Acid Derivatives

MOCCI, RITA;DELOGU, FRANCESCO;PORCHEDDU, ANDREA
2016-01-01

Abstract

An operationally simple, and cost efficient conversion of carboxylic acids into hydroxamic acid derivatives via a high-energy mechanochemical activation is presented. This ball milling methodology was applied to a wide variety of carboxylic acids dramatically improving purification issues associated with this class of molecules, which still remain one of the main bottlenecks of classical methodologies. (Figure presented.).
2016
ball milling; hydroxamic acids; mechanochemical activation; mechanochemistry; O,N-dialkyl hydroxamates; Catalysis; Organic Chemistry
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