Synthesis of quaternary α-benzyl- and α-allyl-α-methylamino cyclobutanones
GHISU, LORENZA;Melis, N;SECCI, FRANCESCO;CABONI, PIERLUIGI;FRONGIA, ANGELO
2016-01-01
Abstract
A simple and practical protocol for the construction of synthetically important quaternary α-benzyl- and α-allyl-α-methylamino cyclobutanones in good to high yield, via a sequential one-pot methylation/sigmatropic rearrangement, has been accomplished for the first time. The quaternary α-alkyl-α-amino cyclobutanones could be further manipulated, affording synthetically interesting scaffolds such as highly substituted tryptamines and cyclobuta-fused indolines.File | Size | Format | |
---|---|---|---|
Tetrahedron 2016 ciclobutanoni.pdf Solo gestori archivio
Type: versione editoriale
Size 919.88 kB
Format Adobe PDF
|
919.88 kB | Adobe PDF | & nbsp; View / Open Request a copy |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.